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HomeProduct name listFerrous Bisglycinate

Ferrous Bisglycinate

Ferrous Bisglycinate Structural

What is Ferrous Bisglycinate?

The Uses of Ferrous Bisglycinate

Ferrous Bisglycinate is used in the fortification of infant formulations and foods.

Background

Ferrous bisglycinate is a chelate that is used as a source of dietary iron. Forming a ring structure when reacting with glycine, ferrous bisglycinate acts as both a chelate and a nutritionally functional . It is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia.

Food additive

Ferrous Bisglycinate (Bisglycine iron(II) salt) is used in the fortification of infant formulations and foods.                

Side Effects

Ferrous Bisglycinate is a novel amino acid iron chelate that is more bioavailable and has fewer gastrointestinal (GI) adverse effects than iron salts. Adverse effects such as constipation, diarrhoea, stomach cramps or upset stomach may occur with Ferrous Bisglycinate. However, usually these effects are temporary and can recover on their own. Iron may cause your faeces to become darker; this effect is harmless. In addition, in the event of a severe allergic reaction to the drug, you need to stop taking it immediately and contact your doctor.

Synthesis

600kg water is added in 1500L reactor, 150kg glycine, 1.5kg carbonyl iron dust, and heating is added under agitation. Stir for 20 minutes to 65 DEG C, then add 550kg ferrous sulfate heptahydrates, 37.5kg maltodextrins, 0.3kg silica, 78 DEG C reaction 30 minutes, reaction complete. Reaction solution sieves heat filtering with 100 mesh stainless sheets of steel, and the filtrate is dried with a pressure spray drying tower, obtained To yellowish-brown green powder Ferrous Bisglycinate 490kg.

Metabolism

Not Available

Biological Uses

Ferrous Bisglycinate is an anti-anemic medication. It replenishes the iron stores in your body. Iron is vital for the formation of new red blood cells and hemoglobin, a substance that gives these cells the ability to transport oxygen.

References

[1] Adelia C Bovell-Benjamin, Lindsay H Allen, Fernando E Viteri. “Iron absorption from ferrous bisglycinate and ferric trisglycinate in whole maize is regulated by iron status123.” American Journal of Clinical Nutrition 71 6 (2000): Pages 1503-1509.

Properties of Ferrous Bisglycinate

Melting point: >162°C (dec.)
Boiling point: 150℃ at 101kPa
Density  1.898 at 20℃
vapor pressure  0-0Pa at 20-25℃
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Aqueous Acid (Slightly)
form  Solid
color  Pale Brown to Brown
Water Solubility  Water: 35.71 mg/mL (176.83 mM)
Stability: Hygroscopic
InChI InChI=1S/2C2H4NO2.Fe/c2*3-1-2(4)5;/h2*3H,1H2,(H,4,5);/q2*-1;+4/p-2

Safety information for Ferrous Bisglycinate

Computed Descriptors for Ferrous Bisglycinate

InChIKey MECJLZIFMOMXPW-UHFFFAOYSA-L
SMILES O=C1CN[Fe+2]2(NCC(=O)[O-]2)[O-]1

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