Ethyl 4-fluorobenzoate

CAS NO.：451-46-7
Empirical Formula: C9H9FO2
Molecular Weight: 168.16
MDL number: MFCD00000351
EINECS: 207-194-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-30 18:52:02

What is Ethyl 4-fluorobenzoate?

Chemical properties

Colorless to pale yellow low melting solid

The Uses of Ethyl 4-fluorobenzoate

Ethyl 4-fluorobenzoate may be used in the synthesis of 4,4′-(1,4-piperazinediyl) bisbenzoic acid ethyl ester.

General Description

Ethyl 4-fluorobenzoate is a clear colorless liquid. The purified [¹⁸F]fluoride is used for solution phase nucleophilic labeling of ethyl [¹⁸F]4-fluorobenzoate. Ethyl 4-fluorobenzoate causes N-arylation of 5-methoxyindole in presence of 18-crown-6 by using microwave-assisted technology.

Properties of Ethyl 4-fluorobenzoate

Melting point:	25-27°C
Boiling point:	210 °C (lit.)
Density	1.146 g/mL at 25 °C (lit.)
refractive index	n20/D 1.486(lit.)
Flash point:	178 °F
storage temp.	Sealed in dry,Room Temperature
form	Low Melting Solid
Specific Gravity	1.146
color	Colorless to pale yellow
Merck	14,4171
BRN	1866794
CAS DataBase Reference	451-46-7(CAS DataBase Reference)
NIST Chemistry Reference	Benzoic acid, 4-fluoro-, ethyl ester(451-46-7)
EPA Substance Registry System	Benzoic acid, 4-fluoro-, ethyl ester (451-46-7)

Safety information for Ethyl 4-fluorobenzoate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.