4-Fluoronitrobenzene

CAS NO.：350-46-9
Empirical Formula: C6H4FNO2
Molecular Weight: 141.1
MDL number: MFCD00007282
EINECS: 206-502-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-18 18:16:58

What is 4-Fluoronitrobenzene?

Chemical properties

yellow liquid

The Uses of 4-Fluoronitrobenzene

1-Fluoro-4-nitrobenzene used as a component of hair dyes, as pharmaceutical intermediates. It is also used for the preparation of novel soluble aromatic polyimides

Synthesis Reference(s)

Journal of the American Chemical Society, 78, p. 6034, 1956 DOI: 10.1021/ja01604a022
Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
Tetrahedron Letters, 30, p. 7199, 1989 DOI: 10.1016/S0040-4039(01)93933-4

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise it from EtOH. [Beilstein 5 H 241, 5 IV 719.]

Properties of 4-Fluoronitrobenzene

Melting point:	21 °C (lit.)
Boiling point:	205 °C (lit.)
Density	1.33 g/mL at 25 °C (lit.)
vapor density	>1 (vs air)
vapor pressure	5.5 mm Hg ( 70 °C)
refractive index	n20/D 1.531(lit.)
Flash point:	182 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Liquid After Melting
color	deep greenish-yellow
Specific Gravity	1.330
Water Solubility	Insoluble in water.
BRN	606923
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference	350-46-9(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, 1-fluoro-4-nitro-(350-46-9)
EPA Substance Registry System	p-Fluoronitrobenzene (350-46-9)

Safety information for 4-Fluoronitrobenzene

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H331:Acute toxicity,inhalation H373:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.