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HomeProduct name list4-Bromofluorobenzene

4-Bromofluorobenzene

Synonym(s):1-Bromo-4-fluorobenzene

  • CAS NO.:460-00-4
  • Empirical Formula: C6H4BrF
  • Molecular Weight: 175
  • MDL number: MFCD00000342
  • EINECS: 207-300-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-31 18:15:48
4-Bromofluorobenzene Structural

What is 4-Bromofluorobenzene?

Chemical properties

clear colorless liquid

The Uses of 4-Bromofluorobenzene

4-Bromofluorobenzene is a dihalogenated benzene used in the preparation of pharmaceutical compounds such as atypical antipsychotic agents.

The Uses of 4-Bromofluorobenzene

1-Bromo-4-fluorobenzene is used as an intermediate in the synthesis of atypical antipsychotic agents.

The Uses of 4-Bromofluorobenzene

4-Bromofluorobenzene can act like a surrogate standard for the:
determination of toxicity of diesel and water accommodated diesel fraction (WAF), towards microalgal species like Pseudokirchneriella subcapitata and Chlorella sp.MM3, using gas chromatography coupled with mass spectrometry (GC-MS).
determination of the chemicals like benzene, toluene, ethylbenzene and xylene (BTEX) and their stable carbon isotopic values, in gasoline contaminated ground-water, using gas chromatography coupled with mass spectrometry (GC-MS).

Definition

ChEBI: 1-bromo-4-fluorobenzene is a member of the class of bromobenzenes that is bromobenzene carrying a fluoro atom at position 4. It is a member of bromobenzenes and a member of monofluorobenzenes.

General Description

Colorless liquid.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Simple aromatic halogenated organic compounds, such as 4-Bromofluorobenzene, are very unreactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Health Hazard

ACUTE/CHRONIC HAZARDS: Irritant.

Flammability and Explosibility

Flammable

Properties of 4-Bromofluorobenzene

Melting point: −16 °C(lit.)
Boiling point: 150 °C(lit.)
Density  1.593 g/mL at 25 °C(lit.)
vapor pressure  4.99hPa at 25℃
refractive index  n20/D 1.527(lit.)
Flash point: 140 °F
storage temp.  2-8°C
solubility  0.136g/l
form  Liquid
color  Clear colorless
Water Solubility  Soluble in water(0.14g/L).
BRN  774102
CAS DataBase Reference 460-00-4(CAS DataBase Reference)
NIST Chemistry Reference p-Bromofluorobenzene(460-00-4)
EPA Substance Registry System p-Bromofluorobenzene (460-00-4)

Safety information for 4-Bromofluorobenzene

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H332:Acute toxicity,inhalation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

Computed Descriptors for 4-Bromofluorobenzene

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