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HomeProduct name listErtugliflozin L-pyroglutamic acid

Ertugliflozin L-pyroglutamic acid

  • CAS NO.:1210344-83-4
  • Empirical Formula: C27H32ClNO10
  • Molecular Weight: 566
  • MDL number: MFCD27956909
  • Update Date: 2024-11-19 15:53:33
Ertugliflozin L-pyroglutamic acid Structural

What is Ertugliflozin L-pyroglutamic acid?

Description

Ertugliflozin L-pyroglutamic acid is a potent, selective, orally active sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor with an IC50 value of 0.877 nM for h-SGLT2.It is the main active ingredient in the tablet ertugliflozin. It is the main active ingredient of ertugliflozin tablets. It is used as an adjunctive therapy for type 2 diabetes.

Chemical properties

Ertugliflozin L-pyroglutamic acid is a white to off-white powder, soluble in ethanol and acetone, slightly soluble in ethyl acetate and acetonitrile, and very slightly soluble in water.

The Uses of Ertugliflozin L-pyroglutamic acid

Ertugliflozin L-pyroglutamic Acid is a reagent in the synthesis of Ertugliflozin (1210344-57-2) a sodium/glucose cotransporter 2 (SGLT2) inhibitor used to treat type 2 diabetes.

brand name

STEGLATRO

Properties of Ertugliflozin L-pyroglutamic acid

storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  DMSO: ≥ 125 mg/mL (220.85 mM)
form  Solid
color  White to off-white

Safety information for Ertugliflozin L-pyroglutamic acid

Computed Descriptors for Ertugliflozin L-pyroglutamic acid

InChIKey YHIUPZFKHZTLSH-NCRAORDPNA-N
SMILES C([C@@H]1CCC(=O)N1)(=O)O.O[C@@H]1[C@H]([C@H](O)[C@]2(CO)CO[C@@]1(C1C=CC(Cl)=C(CC3C=CC(OCC)=CC=3)C=1)O2)O |&1:1,10,11,12,14,19,r|

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