Ergonovine maleate
Synonym(s):Ergometrine maleate salt;Ergonovine maleate salt
- CAS NO.：129-51-1
- Empirical Formula: C23H27N3O6
- Molecular Weight: 441.48
- MDL number: MFCD00672896
- EINECS: 204-953-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is Ergonovine maleate?
Chemical properties
white solid
The Uses of Ergonovine maleate
Ergonovine is an oxytocic, stimulates contraction of uterine muscle; partial agonist at serotonergic and dopaminergic receptors in CNS; selective, potent antagonist at smooth muscle serotonergic receptors.
Definition
ChEBI: A maleate salt resulting form the reaction of equimolar amounts of maleic acid and ergometrine. It is used in the active management of the third stage of labour, and to prevent or treat postpartum of postabortal haemorrhage caused by uterine atony: by main aining uterine contraction and tone, blood vessels in the uterine wall are compressed and blood flow reduced.
brand name
Ergotrate Maleate (Lilly).
Properties of Ergonovine maleate
| Melting point: | 167 °C (decomp) |
| Boiling point: | 552.4°C (rough estimate) |
| alpha | D25 +48 to +57° |
| Density | 1.2948 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | −20°C |
| Stability: | Stable, but may be heat sensitive - store at -20 C. Incompatible with strong oxidizing agents. |
Safety information for Ergonovine maleate
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P403+P233:Store in a well-ventilated place. Keep container tightly closed. |
Computed Descriptors for Ergonovine maleate
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