Eperisone
- CAS NO.:64840-90-0
- Empirical Formula: C17H25NO
- Molecular Weight: 259.39
- MDL number: MFCD00867679
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-12 16:52:38
What is Eperisone?
Originator
Myonal,Eisai,Japan,1983
Definition
ChEBI: 1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one is an aromatic ketone that is N-propylpiperidine in which a hydrogen at positon 2 of the propyl group is replaced by a p-ethylbenzoyl group. It is a member of piperidines and an aromatic ketone.
Manufacturing Process
To 60 ml of isopropanol, there are introduced 120 g of 4-ethyl-propiophenone, 28.8g of p-formaldehyde and 107 g of piperidine hydrochloride, and the resulting mixture is heated to reflux on an oil bath with stirring. The heating is continued, and when the reaction mixture solidifies, the state being a sign of completion of the reaction, there are added 500 ml of acetone thereinto. The solidified mass is pulverized by crush, recovered by filtration and washed with acetone. 144 g of the crude dry crystalline substance is thus obtained, which is the hydrochloride of the purposed product. The hydrochloride is recrystallized from isopropanol, and there are obtained the crystalline needles having the melting point of 170°C to 172°C.
Therapeutic Function
Muscle relaxant
Properties of Eperisone
Boiling point: | 386.8±35.0 °C(Predicted) |
Density | 0.994±0.06 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
pka | 8.46±0.10(Predicted) |
CAS DataBase Reference | 64840-90-0(CAS DataBase Reference) |
Safety information for Eperisone
Computed Descriptors for Eperisone
New Products
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