2,2,6,6-Tetramethyl-4-piperidinol
Synonym(s):4-Hydroxy-2,2,6,6-tetramethylpiperidine
- CAS NO.：2403-88-5
- Empirical Formula: C9H19NO
- Molecular Weight: 157.25
- MDL number: MFCD00005983
- EINECS: 219-291-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-29 17:07:33
What is 2,2,6,6-Tetramethyl-4-piperidinol?
Chemical properties
white to slightly beige crystalline powder
The Uses of 2,2,6,6-Tetramethyl-4-piperidinol
2,2,6,6-tetramethyl-4-piperidinol has been used to study the irradiation of Camptothecin (CPT) in aerated dimethylsulfoxide (DMSO) solution that leads to formation of singlet oxygen.
The Uses of 2,2,6,6-Tetramethyl-4-piperidinol
An intermediate in the preparation of Piperidinyloxy free radical derivatives.
Synthesis Reference(s)
The Journal of Organic Chemistry, 37, p. 2050, 1972 DOI: 10.1021/jo00977a047
Purification Methods
The piperidine crystallises from water as a hydrate and crystallises from dry ether or *C6H6 as the anhydrous base. The hydrochloride has m 282-284o (from EtOH/H2O), and the formate has m 207o(dec, from EtOH/EtOAc). [Mailey & Day J Org Chem 22 1061 1957, Beilstein 21 I 195, 21 III/IV 146, 21/1 V 159.]
Properties of 2,2,6,6-Tetramethyl-4-piperidinol
| Melting point: | 129-131 °C(lit.) |
| Boiling point: | 212-215 °C(lit.) |
| Density | 1.085 |
| refractive index | 1.4248 (estimate) |
| Flash point: | 212-215°C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | methanol: 0.1 g/mL, clear |
| pka | 14.99±0.60(Predicted) |
| form | Crystals, Crystalline Powder and/or Chunks |
| color | White to off-white or slightly beige |
| PH | 11.2 (4g/l, H2O, 20℃) |
| Water Solubility | 130 g/L (23 ºC) |
| BRN | 105039 |
| CAS DataBase Reference | 2403-88-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Piperidinol, 2,2,6,6-tetramethyl-(2403-88-5) |
| EPA Substance Registry System | 4-Piperidinol, 2,2,6,6-tetramethyl- (2403-88-5) |
Safety information for 2,2,6,6-Tetramethyl-4-piperidinol
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2,6,6-Tetramethyl-4-piperidinol
| InChIKey | VDVUCLWJZJHFAV-UHFFFAOYSA-N |
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
4-Hydroxy-2,2,6,6-tetramethylpiperidine CAS 2403-88-5View Details
2403-88-5 -
2,2,6,6-Tetramethyl-4-piperidinol CAS 2403-88-5View Details
2403-88-5 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
1784294-80-9 98%View Details
1784294-80-9 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.