Dodecyltriphenylphosphonium bromide
- CAS NO.：15510-55-1
- Empirical Formula: C30H40BrP
- Molecular Weight: 511.52
- MDL number: MFCD00031546
- EINECS: 239-538-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is Dodecyltriphenylphosphonium bromide?
Description
Dodecyl-TPP (15510-55-1) is a mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis.1 Potently eradicates cancer stem cells (50 nm to 1 mM) selectively over normal cells1. Synergizes with FDA-approved drugs such as doxycycline and niclosamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria.2
What are the applications of Application
Dodecyltriphenylphosphonium bromide is used in studies of anticorrosion efficiency of nanocomposite coatings
Definition
ChEBI: An organic bromide salt that containing equal numbers of dodecyl(triphenyl)phosphonium cations and bromide anions.
References
References:
Properties of Dodecyltriphenylphosphonium bromide
| Melting point: | 85-88 °C(lit.) |
| storage temp. | RT |
| solubility | Soluble in DMSO (50 mg/ml) or ethanol (25 mg/mL) |
| form | solid |
| color | White |
| Sensitive | Hygroscopic |
| BRN | 3581921 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
| CAS DataBase Reference | 15510-55-1(CAS DataBase Reference) |
Safety information for Dodecyltriphenylphosphonium bromide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Dodecyltriphenylphosphonium bromide
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