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HomeProduct name listDodecyltriphenylphosphonium bromide

Dodecyltriphenylphosphonium bromide

  • CAS NO.:15510-55-1
  • Empirical Formula: C30H40BrP
  • Molecular Weight: 511.52
  • MDL number: MFCD00031546
  • EINECS: 239-538-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
Dodecyltriphenylphosphonium bromide Structural

What is Dodecyltriphenylphosphonium bromide?

Description

Dodecyl-TPP (15510-55-1) is a mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis.1 Potently eradicates cancer stem cells (50 nm to 1 mM) selectively over normal cells1. Synergizes with FDA-approved drugs such as doxycycline and niclosamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria.2

What are the applications of Application

Dodecyltriphenylphosphonium bromide is used in studies of anticorrosion efficiency of nanocomposite coatings

Definition

ChEBI: An organic bromide salt that containing equal numbers of dodecyl(triphenyl)phosphonium cations and bromide anions.

References

References:

Properties of Dodecyltriphenylphosphonium bromide

Melting point: 85-88 °C(lit.)
storage temp.  RT
solubility  Soluble in DMSO (50 mg/ml) or ethanol (25 mg/mL)
form  solid
color  White
Sensitive  Hygroscopic
BRN  3581921
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
CAS DataBase Reference 15510-55-1(CAS DataBase Reference)

Safety information for Dodecyltriphenylphosphonium bromide

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for Dodecyltriphenylphosphonium bromide

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