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HomeProduct name listSodium N-lauroylsarcosinate

Sodium N-lauroylsarcosinate

Synonym(s):Sodium lauroyl sarcosinate;Sarcosyl;N-Lauryl sarcosine sodium salt;Sarcosyl, Sodium lauroylsarcosinate;Sarkosyl NL

  • CAS NO.:137-16-6
  • Empirical Formula: C15H28NO3.Na
  • Molecular Weight: 293.38
  • MDL number: MFCD00042728
  • EINECS: 205-281-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-24 21:11:45
Sodium N-lauroylsarcosinate Structural

What is Sodium N-lauroylsarcosinate?

Chemical properties

white powder

The Uses of Sodium N-lauroylsarcosinate

Detergent, foaming agent, antienzyme for dentifrices: King, US 2689170 (1954 to Colgate-Palmolive).

The Uses of Sodium N-lauroylsarcosinate

N-Lauroylsarcosine is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase. It is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming). It has been used to indicate paramagnetic anisotropy sign change in micelle mesophage. Inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungi static agent in aqueous dispersion (1%).

The Uses of Sodium N-lauroylsarcosinate

Suitable for

  • solubilization and separation of membrane proteins
  • lysis of cells during the isolation of RNA
  • inhibition of hexokinase

What are the applications of Application

Lauroylsarcosine, Sodium Salt is an ionic detergent used to purify membrane proteins

General Description

N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

N-Lauroylsarcosine is an anionic surfactant which also has protein denaturant potency. In addition, it has been shown as a microbicide for sexually transmitted diseases.

Properties of Sodium N-lauroylsarcosinate

Melting point: 46 °C
Density  1.033 g/mL at 20 °C
vapor pressure  0.02 hPa (20 °C)
RTECS  MC0598960
Flash point: 267℃
storage temp.  room temp
solubility  H2O: 1 M at 20 °C, clear, colorless
form  Powder
color  White
Specific Gravity 1.03 (20/4℃)
Odor at 100.00?%. bland
PH 7.0-9.0 (25℃, 1M in H2O)
Water Solubility  Soluble in water (293 g/L).
Sensitive  Hygroscopic
λmax λ: 260 nm Amax: 0.2
λ: 280 nm Amax: 0.06
Merck  14,4368
BRN  5322974
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 137-16-6(CAS DataBase Reference)
EPA Substance Registry System Sodium N-lauroylsarcosinate (137-16-6)

Safety information for Sodium N-lauroylsarcosinate

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H330:Acute toxicity,inhalation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Sodium N-lauroylsarcosinate

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