Diethylamine hydrochloride

Synonym(s):Diethylamine hydrochloride;Diethylammonium chloride;Ehrlich’s reagent III;Loeffler’s Methylene Blue;Methylene blue stain

CAS NO.：660-68-4
Empirical Formula: C4H12ClN
Molecular Weight: 109.6
MDL number: MFCD00012499
EINECS: 211-541-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-30 18:52:02

What is Diethylamine hydrochloride?

Chemical properties

white to off-white crystals or crystalline powder

The Uses of Diethylamine hydrochloride

Diethylamine hydrochloride acts as a precursor of atrazine and lysergic acid diethylamide. It is also used as a reactant in the production of dyes and pharmaceutical compounds such as ranitidine. Further, it is used in Mannich reaction with paraformaldehyde. In addition to this, it is employed in the synthesis of diethylaminoethyl (DEAE) cottons by reacting with cotton cellulose in the presence of sodium hydroxide.

Flammability and Explosibility

Not classified

Purification Methods

Crystallise salt from absolute EtOH. Also crystallise it from dichloroethane/MeOH. Hygroscopic. [Beilstein 4 III 113.]

Properties of Diethylamine hydrochloride

Melting point:	227-230 °C(lit.)
Boiling point:	320-330 °C
Density	1.0 g/mL at 20 °C
vapor pressure	<0.00001 hPa (20 °C)
refractive index	1.5320 (estimate)
Flash point:	320-330°C
storage temp.	Store below +30°C.
solubility	H2O: soluble50mg/mL, clear, colorless
form	Liquid
Specific Gravity	1.0475 (21℃)
color	White to off-white
PH	4.5-6.5 (10g/l, H2O, 20℃)
Water Solubility	soluble
Sensitive	Hygroscopic
Merck	14,3111
BRN	3590084
CAS DataBase Reference	660-68-4(CAS DataBase Reference)
EPA Substance Registry System	Diethylamine hydrochloride (660-68-4)

Safety information for Diethylamine hydrochloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H311:Acute toxicity,dermal H314:Skin corrosion/irritation H317:Sensitisation, Skin H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.