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HomeProduct name listDeracoxib

Deracoxib

Synonym(s):4-[3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzenesulfonamide;4-[5-(3-Fluoro-4-methoxyphenyl)-3-(difluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide;SC-046;SC-46;SC-59046

  • CAS NO.:169590-41-4
  • Empirical Formula: C17H14F3N3O3S
  • Molecular Weight: 397.37
  • MDL number: MFCD09837763
  • EINECS: 807-307-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-09-04 16:42:00
Deracoxib Structural

What is Deracoxib?

The Uses of Deracoxib

Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low dose s, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation.

The Uses of Deracoxib

Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low doses, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation.

Definition

ChEBI: A member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3, and 5 by 4-sulfamoylphenyl, difluoromethyl and 3-fluoro-4-methoxyphenyl groups, respectively. A selective cyclooxygenase 2 inhibitor, it is us d in veterinary medicine for the control of pain and inflammation associated with osteoarthritis in dogs.

Veterinary Drugs and Treatments

Deracoxib is indicated for the treatment of post-operative pain (higher dose, 7 day maximum), and for the treatment of pain and inflammation associated with osteoarthritis (lower dose, ongoing dosing) in dogs.
Like piroxicam, deracoxib is of interest in adjunctive treatment of transitional cell carcinoma of the bladder; investigations into this use are ongoing.

Properties of Deracoxib

Melting point: 159-161°
Boiling point: 575.5±60.0 °C(Predicted)
Density  1.48
storage temp.  2-8°C
solubility  Acetonitrile (Slightly), DMSO (Slightly)
form  Solid
pka 9.69±0.10(Predicted)
color  Light Brown

Safety information for Deracoxib

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral

Computed Descriptors for Deracoxib

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