Deracoxib
Synonym(s):4-[3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzenesulfonamide;4-[5-(3-Fluoro-4-methoxyphenyl)-3-(difluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide;SC-046;SC-46;SC-59046
- CAS NO.:169590-41-4
- Empirical Formula: C17H14F3N3O3S
- Molecular Weight: 397.37
- MDL number: MFCD09837763
- EINECS: 807-307-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-04 16:42:00
What is Deracoxib?
The Uses of Deracoxib
Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low dose s, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation.
The Uses of Deracoxib
Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low doses, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation.
Definition
ChEBI: A member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3, and 5 by 4-sulfamoylphenyl, difluoromethyl and 3-fluoro-4-methoxyphenyl groups, respectively. A selective cyclooxygenase 2 inhibitor, it is us d in veterinary medicine for the control of pain and inflammation associated with osteoarthritis in dogs.
Veterinary Drugs and Treatments
Deracoxib is indicated for the treatment of post-operative pain
(higher dose, 7 day maximum), and for the treatment of pain and
inflammation associated with osteoarthritis (lower dose, ongoing
dosing) in dogs.
Like piroxicam, deracoxib is of interest in adjunctive treatment
of transitional cell carcinoma of the bladder; investigations into this
use are ongoing.
Properties of Deracoxib
Melting point: | 159-161° |
Boiling point: | 575.5±60.0 °C(Predicted) |
Density | 1.48 |
storage temp. | 2-8°C |
solubility | Acetonitrile (Slightly), DMSO (Slightly) |
form | Solid |
pka | 9.69±0.10(Predicted) |
color | Light Brown |
Safety information for Deracoxib
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for Deracoxib
Abamectin manufacturer
Alivira Animal Health Ltd
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