D(-)Prolinol
Synonym(s):(R)-(−)-2-(Hydroxymethyl)pyrrolidine;(R)-(−)-2-Pyrrolidinemethanol;D -Prolinol
- CAS NO.：68832-13-3
- Empirical Formula: C5H11NO
- Molecular Weight: 101.15
- MDL number: MFCD00064321
- EINECS: 629-147-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-21 22:41:43
What is D(-)Prolinol?
Chemical properties
Colorless to light yellow liqui
The Uses of D(-)Prolinol
(2R)-2-Pyrrolidinemethanol is used in the synthesis of potent selective 5-HT7 antagonists.
Definition
ChEBI: The D-enantiomer of prolinol. Metabolite observed in cancer metabolism.
Properties of D(-)Prolinol
| Boiling point: | 74-76 °C2 mm Hg(lit.) |
| alpha | -31 º (c=1, toluene) |
| Density | 1.036 g/mL at 20 °C(lit.) |
| refractive index | n |
| Flash point: | 187 °F |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly), Toluene (Slightly) |
| pka | 14.77±0.10(Predicted) |
| form | Solution |
| color | Clear to slightly hazy colorless to amber |
| Specific Gravity | 1.025 |
| optical activity | [α]20/D 31°, c = 1 in toluene |
| Sensitive | Air Sensitive |
| BRN | 1523669 |
| CAS DataBase Reference | 68832-13-3(CAS DataBase Reference) |
Safety information for D(-)Prolinol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for D(-)Prolinol
| InChIKey | HVVNJUAVDAZWCB-RXMQYKEDSA-N |
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