D-Homophenylalanine
Synonym(s):(R)-2-Amino-4-phenylbutyric acid
- CAS NO.：82795-51-5
- Empirical Formula: C10H13NO2
- Molecular Weight: 179.22
- MDL number: MFCD00063091
- EINECS: 1308068-626-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-26 15:15:06
What is D-Homophenylalanine?
Chemical properties
BEIGE POWDER
The Uses of D-Homophenylalanine
D-Homophenylalanine is used in peptide synthesis as an amino acid protection monomer.
Preparation
Synthesis of D-Homophenylalanine: To obtain D-homophenylalanine in high yield by treating 5- benzylmethylhydantoin with a microorganism belonging to the genus Pseudomonas or a 5-hydantoin decomposition-type enzyme derived from the microorganism.
Properties of D-Homophenylalanine
| Melting point: | >300 °C (lit.) |
| Boiling point: | 311.75°C (rough estimate) |
| alpha | -45 º (c=1, 3N HCl 19 ºC) |
| Density | 1.1248 (rough estimate) |
| refractive index | -45 ° (C=1, 3mol/L HCl) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Aqueous Acid (Sparingly), Aqueous Base (Slightly) |
| form | Solid |
| pka | 2.32±0.10(Predicted) |
| color | White to Off-White |
| BRN | 4675530 |
| CAS DataBase Reference | 82795-51-5(CAS DataBase Reference) |
Safety information for D-Homophenylalanine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H226:Flammable liquids H302:Acute toxicity,oral H311:Acute toxicity,dermal H314:Skin corrosion/irritation H317:Sensitisation, Skin H334:Sensitisation, respiratory H370:Specific target organ toxicity, single exposure H373:Specific target organ toxicity, repeated exposure H401:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P284:Wear respiratory protection. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for D-Homophenylalanine
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