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HomeProduct name listD(+)-Carnitine

D(+)-Carnitine

D(+)-Carnitine Structural

What is D(+)-Carnitine?

Chemical properties

white to light yellow crystal powde

The Uses of D(+)-Carnitine

Essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado.

Definition

ChEBI: The (S)-enantiomer of carnitine.

Purification Methods

The S(L) isomer is levocarnitine, Vitamin B7. The R or S isomers crystallise from EtOH/Me2CO (hygroscopic). The R or S hydrochlorides crystallise from hot EtOH or EtOH/Et2O and have m 142o(dec). The RS-isomer crystallises from hot EtOH (hygroscopic). The RS hydrochloride crystallises in needles from hot EtOH and has m 196o(dec). [(±) Mazzetti & Lemmon J Org Chem 22 228 1957, Beilstein 4 H 513, 4 I 548, 4 II 937-8, 4 III 1632-5, 4 IV 3185.]

Properties of D(+)-Carnitine

Melting point: 197 °C
Boiling point: 287.5°C (rough estimate)
alpha  D +30.9°
Density  1.1587 (rough estimate)
refractive index  1.4500 (estimate)
storage temp.  Inert atmosphere,2-8°C
solubility  Methanol (Slightly), Water (Slightly)
form  Solid
color  White to Off-White
Merck  13,1862
Stability: Hygroscopic

Safety information for D(+)-Carnitine

Computed Descriptors for D(+)-Carnitine

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