Cryptochlorogenic acid

Synonym(s):4-O-(3,4-Dihydroxycinnamoyl)-D-quinic acid;4-O-Caffeoylquinic acid;Cryptochlorogenic acid

CAS NO.：905-99-7
Empirical Formula: C16H18O9
Molecular Weight: 354.31
MDL number: MFCD10566638
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-31 13:32:20

What is Cryptochlorogenic acid?

The Uses of Cryptochlorogenic acid

Cryptochlorogenic acid may be used as a reference standard in the determination of cryptochlorogenic acid in the leaves of Hibiscus sabdariffa using high performance liquid chromatography coupled with mass spectrometry (HPLC-MS).

The Uses of Cryptochlorogenic acid

4-O-Caffeoylquinic acid has been used as a reference compound for the quantification in high performance liquid chromatography-diode array detector (HPLC-DAD).

Definition

ChEBI: A cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 4-hydroxy group of (+)-quinic acid.

General Description

Cryptochlorogenic acid is a polyphenol, found in a variety of plants, which plays a crucial role in protection against various age-related diseases.

Biochem/physiol Actions

4-O-Caffeoylquinic acid (4-CQA) is a major active antioxidant marker in mulberry leaf extract. It is an inhibitor of ferroptosis hence, it is recognized as a potent anti-diabetic agent. 4-CQA plays an important role in the upregulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway.

Properties of Cryptochlorogenic acid

Boiling point:	694.9±55.0 °C(Predicted)
Density	1.65
storage temp.	2-8°C
solubility	DMSO : 50 mg/mL (141.12 mM; Need ultrasonic)
form	neat
pka	4.07±0.50(Predicted)
form	Solid
color	White-pale yellow
optical activity	[α]/D -76.0±5.0°, c = 0.5 in H2O
Stability:	Hygroscopic

Safety information for Cryptochlorogenic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.