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HomeProduct name listCresol Red

Cresol Red

  • CAS NO.:1733-12-6
  • Empirical Formula: C21H18O5S
  • Molecular Weight: 382.43
  • MDL number: MFCD00005878
  • EINECS: 217-064-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-05 19:05:58
Cresol Red Structural

What is Cresol Red?

Chemical properties

Dark green or brown-red powder

The Uses of Cresol Red

Cresol red is commonly used with lead acetate for the detection of urease after PAGE. It is also used as an indicator with the following transition intervals: pH 1.8 (orange) to pH 2.0 (yellow); pH 7.0 (yellow) to pH 8.8 (violet). Cresol Red is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) electrophoresis. In agarose, Cresol Red runs with an apparent molecular size of approx. 125 bp DNA. Cresol Red does not inhibit Taq polymerase.

The Uses of Cresol Red

Acid-base indicator.

What are the applications of Application

Cresol red is a stain commonly used with lead acetate for detection of urease after PAGE

Definition

ChEBI: A member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxy-5-methylphenyl groups.

Purification Methods

Crystallise it from glacial acetic acid. Dry it in air. Dissolve it in aqueous 5% NaHCO3 solution and precipitate it from a hot solution by dropwise addition of aqueous HCl. Repeat the procedure till the UVmax does not increase. [Beilstein 19 IV 1133.]

Properties of Cresol Red

Melting point: 290 °C
Boiling point: 479.59°C (rough estimate)
Density  0.998 g/cm3
refractive index  1.5300 (estimate)
storage temp.  Store at +5°C to +30°C.
solubility  Solubility Sparingly soluble in water; soluble in ethanol
form  Powder
pka 1.0(at 25℃)
color  Dark green or brown-red
PH Range 7.2(YELLOW)--8.8(PURPLISH RED)
PH 7.2~8.8
Water Solubility  soluble
λmax 570nm, 367nm, 432nm
Merck  14,2578
BRN  343399
Major Application Display device, optical sensors, combustion gas detection system, inks, correction fluid, diapers, toothpaste, identifying fresh and stale rice, food storage, determine glucose in dialysis solution, monitor metabolic activity of microorganisms, detect bacterialinfection, psychoactive drugs, dental impression material
EPA Substance Registry System Cresol Red (1733-12-6)

Safety information for Cresol Red

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for Cresol Red

InChIKey ASMGMVUGPNODGX-UHFFFAOYSA-N

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