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HomeProduct name listCPPG

CPPG

Synonym(s):(R,S)-α-Cyclopropyl-4-phosphonophenylglycine

CPPG Structural

What is CPPG?

The Uses of CPPG

(RS)-CPPG is the most potent group II/III mGluR antagonist.

What are the applications of Application

(RS)-CPPG is the most potent group II/III mGluR antagonist

Definition

ChEBI: 2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid is an alpha-amino acid.

Biological Activity

Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC 50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (K b = 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™ .

storage

Room temperature

Properties of CPPG

storage temp.  Store at RT
solubility  H2O: >5mg/mL
form  Solid
color  white to beige

Safety information for CPPG

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral

Computed Descriptors for CPPG

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