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HomeProduct name listCOLCHICOSIDE

COLCHICOSIDE

  • CAS NO.:477-29-2
  • Empirical Formula: C27H33NO11
  • Molecular Weight: 547.554
  • MDL number: MFCD01736974
  • EINECS: 207-513-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-05 20:55:42
COLCHICOSIDE Structural

What is COLCHICOSIDE?

Chemical properties

Pale Yellow Solid

The Uses of COLCHICOSIDE

A significantly toxic Colchicine analog with no anti-inflammatory properties.

Definition

ChEBI: Colchicoside is a carbotricyclic compound, an alkaloid and a member of acetamides.

Purification Methods

Purify colchicoside by chromatography through alumina and eluting with CHCl3, then recrystallising from Me2CO, m 275-280o (after releasing solvent at 180o). It also crystallises from EtOH; see colchicine. The tetraacetate has m 175-177o, [] D 15 -57o (c 1, CHCl3). [Bellet et al. Ann Pharm Fr 10 241 1952, Chem Abstr 47 3323 1953, Beilstein 14 IV 946 for colchicine.]

Properties of COLCHICOSIDE

Melting point: 194-197°C
Boiling point: 620.17°C (rough estimate)
Density  1.3430 (rough estimate)
refractive index  1.6400 (estimate)
storage temp.  Refrigerator
solubility  DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form  A crystalline solid
pka 12.74±0.70(Predicted)
color  Light yellow to yellow

Safety information for COLCHICOSIDE

Computed Descriptors for COLCHICOSIDE

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