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HomeProduct name listtrimethylcolchicinic acid methyl ether

trimethylcolchicinic acid methyl ether

trimethylcolchicinic acid methyl ether Structural

What is trimethylcolchicinic acid methyl ether?

Chemical properties

Yellow Solid

The Uses of trimethylcolchicinic acid methyl ether

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

What are the applications of Application

N-Deacetylcolchicine is it binds to tubulin thereby preventing its polymerization

Definition

ChEBI: Deacetylcolchicine is a carbotricyclic compound, an alkaloid and a member of acetamides.

Properties of trimethylcolchicinic acid methyl ether

Boiling point: 490.03°C (rough estimate)
Density  1.2532 (rough estimate)
refractive index  1.5614 (estimate)
storage temp.  -20°C Freezer, Under Inert Atmosphere
solubility  DMSO: 25mg/mL; Ethanol: 25mg/mL
form  A crystalline solid
pka 8.62±0.40(Predicted)

Safety information for trimethylcolchicinic acid methyl ether

Computed Descriptors for trimethylcolchicinic acid methyl ether

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