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HomeProduct name listCIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID

CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID

CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID Structural

What is CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID?

The Uses of CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID

CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID is an ω-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.

The Uses of CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID

A fatty acid use to inhibit platelet aggregation

The Uses of CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID

all-cis-7,10,13,16,19-Docosapentaenoic Acid, also known as DPA, is a fatty acid derived from fish oils that potently inhibits platelet aggregation. DPA has been reported to block the cyclooxygenase pathway and stimulate the lipoxygenase pathway, which results in effective platelet aggregation inhibition. Peripheral blood mononuclear cell research demonstrates that DPA diminishes cyclooxygenase-2 levels intracellularly and inhibits pro-inflammatory prostaglandin E2 production.

What are the applications of Application

7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid is a fatty acid shown to inhibit platelet aggregation

Definition

ChEBI: The all-cis-isomer of a C22 polyunsaturated fatty acid having five double bonds in the 7-, 10-, 13-, 16- and 19-positions.

General Description

A Certified Spiking Solution? suitable for use in mass spectrometry-based fatty acid testing applications such as assessment of cardiovascular disease risk and fatty acid deficiency, and detection and quantification of docosapentaenoic acid in nutraceuticals and dietary supplements. Docosapentaenoic acid (cis-7,10,13,16,19), also known as DPA, is an omega-3 fatty acid associated with neurological and ocular health benefits. Studies suggests that DPA as well as other fatty acids can serve as biomarkers for cardiovascular disease, and nutritional and metabolic disorders.

Properties of CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID

Boiling point: 442.2±24.0 °C(Predicted)
Density  0.932±0.06 g/cm3(Predicted)
Flash point: 14℃
storage temp.  -20°C
solubility  0.1 M Na2CO3: 1.7 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: Miscible
form  liquid
pka 4.76±0.10(Predicted)
color  Colorless to light yellow
EPA Substance Registry System Docosapentaenoic (24880-45-3)

Safety information for CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H225:Flammable liquids
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P240:Ground/bond container and receiving equipment.
P241:Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242:Use only non-sparking tools.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID

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