CI 46025

CAS NO.：135-49-9
Empirical Formula: C15H16ClN3
Molecular Weight: 273.76
MDL number: MFCD00012661
EINECS: 205-194-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:23

What is CI 46025?

Chemical properties

copper or brown-red crystalline powder

The Uses of CI 46025

Acridine Yellow G may be useful in the preparations of aptamers for targeting coagulation factor XIII for treatment of thrombosis.

Biochem/physiol Actions

Acridine Yellow G (AYG) is an organic dye with photophysical properties. It is widely used in optics, medicine and photovoltaic cells. AYG has been used as a solar photocatalyst to increase biodegradability and remove ferulic acid, a target pollutant from wastewater. It retards the growth of glioblastoma via dual inhibition of epidermal growth factor receptor and protein kinase c kinases.

Purification Methods

Note that the hydrochloride is normally called Acridine Yellow G and not the free base. The free base recrystallises from 1:1 *benzene/methanol, or from 800 parts of EtOH. It is converted to the sparingly soluble hydrochloride with dilute HCl, filtered off and dried. [Albert J Chem Soc 248 1947, Beilstein 22 III/IV 5499, 22/11 V 340.]

Properties of CI 46025

Melting point:	400 °C
storage temp.	room temp
pka	pKa -3.0(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);0.5(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);8.9(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain)
Colour Index	46025
color	Dark orange to brown crystalline powder
EPA Substance Registry System	3,6-Acridinediamine, 2,7-dimethyl-, monohydrochloride (135-49-9)

Safety information for CI 46025

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H351:Carcinogenicity
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention.