Chlorhexidine hydrochloride
Synonym(s):1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide);Chlorhexidine dihydrochloride;Lisium
- CAS NO.:3697-42-5
- Empirical Formula: C22H32Cl4N10
- Molecular Weight: 578.37
- MDL number: MFCD00068998
- EINECS: 223-026-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-24 21:11:45
What is Chlorhexidine hydrochloride?
Chemical properties
White Crystalline Solid
The Uses of Chlorhexidine hydrochloride
Chlorhexidine hydrochloride is a bisbiguanide with bacteriostatic activity. Antiseptic; disinfectant.
The Uses of Chlorhexidine hydrochloride
antibacterial (topical), disinfectant
The Uses of Chlorhexidine hydrochloride
chlorhexidine dihydrochloride is a preservative, it functions primarily as an anti-microbial, helping control the proliferation of bacteria, fungi, or yeast in a product.
Definition
ChEBI: Chlorhexidine hydrochloride is a member of guanidines.
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Flammability and Explosibility
Not classified
Chemical properties
Chlorhexidine Hydrochloride occurs as awhite,crystalline powder. It is odorless,and has a bittertaste. It is soluble in formic acid,slightly soluble in methanoland in warm methanol, and practically insoluble in water , in ethanol and in diethyl ether. It is gradually colored by light.
Mechanism of action
Chlorhexidine hydrochloride has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought.It is also useful against fungi and enveloped viruses, though this has not been extensively investigated.
Properties of Chlorhexidine hydrochloride
Melting point: | 111-116 °C |
Density | 1.284[at 20℃] |
vapor pressure | 0.003Pa at 25℃ |
storage temp. | 2-8°C |
solubility | Sparingly soluble in water and in propylene glycol, very slightly soluble in ethanol (96 per cent). |
form | neat |
form | Solid |
color | White to Off-White |
Odor | odorless |
Water Solubility | 0.06 g/100 mL (20 ºC) |
Merck | 14,2091 |
EPA Substance Registry System | Chlorhexidine dihydrochloride (3697-42-5) |
Safety information for Chlorhexidine hydrochloride
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Environment GHS09 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P391:Collect spillage. Hazardous to the aquatic environment P501:Dispose of contents/container to..… |
Computed Descriptors for Chlorhexidine hydrochloride
InChIKey | WJLVQTJZDCGNJN-UHFFFAOYSA-N |
Abamectin manufacturer
Chynops Pharma
Dishman Carbogen Amcis Ltd (Dishman Group)
Alex Pharmachem Pvt. Ltd
Basic Pharma Life Science Pvt Ltd
Kenoor Organics Private Limited
Organo Chem (India)
Salicylates and Chemicals Pvt. Ltd.
Smaart Pharmaceutticals
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