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HomeProduct name listChlorhexidine hydrochloride

Chlorhexidine hydrochloride

Synonym(s):1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide);Chlorhexidine dihydrochloride;Lisium

  • CAS NO.:3697-42-5
  • Empirical Formula: C22H32Cl4N10
  • Molecular Weight: 578.37
  • MDL number: MFCD00068998
  • EINECS: 223-026-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-24 21:11:45
Chlorhexidine hydrochloride Structural

What is Chlorhexidine hydrochloride?

Chemical properties

White Crystalline Solid

The Uses of Chlorhexidine hydrochloride

Chlorhexidine hydrochloride is a bisbiguanide with bacteriostatic activity. Antiseptic; disinfectant.

The Uses of Chlorhexidine hydrochloride

antibacterial (topical), disinfectant

The Uses of Chlorhexidine hydrochloride

chlorhexidine dihydrochloride is a preservative, it functions primarily as an anti-microbial, helping control the proliferation of bacteria, fungi, or yeast in a product.

Definition

ChEBI: Chlorhexidine hydrochloride is a member of guanidines.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Flammability and Explosibility

Not classified

Chemical properties

Chlorhexidine Hydrochloride occurs as awhite,crystalline powder. It is odorless,and has a bittertaste. It is soluble in formic acid,slightly soluble in methanoland in warm methanol, and practically insoluble in water , in ethanol and in diethyl ether. It is gradually colored by light.

Mechanism of action

Chlorhexidine hydrochloride has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought.It is also useful against fungi and enveloped viruses, though this has not been extensively investigated.

Properties of Chlorhexidine hydrochloride

Melting point: 111-116 °C
Density  1.284[at 20℃]
vapor pressure  0.003Pa at 25℃
storage temp.  2-8°C
solubility  Sparingly soluble in water and in propylene glycol, very slightly soluble in ethanol (96 per cent).
form  neat
form  Solid
color  White to Off-White
Odor odorless
Water Solubility  0.06 g/100 mL (20 ºC)
Merck  14,2091
EPA Substance Registry System Chlorhexidine dihydrochloride (3697-42-5)

Safety information for Chlorhexidine hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P391:Collect spillage. Hazardous to the aquatic environment
P501:Dispose of contents/container to..…

Computed Descriptors for Chlorhexidine hydrochloride

InChIKey WJLVQTJZDCGNJN-UHFFFAOYSA-N

Abamectin manufacturer

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