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HomeProduct name listCefoselis sulfate

Cefoselis sulfate

  • CAS NO.:122841-12-7
  • Empirical Formula: C19H24N8O10S3
  • Molecular Weight: 620.63
  • MDL number: MFCD01940015
  • EINECS: 1533716-785-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-07 21:39:59
Cefoselis sulfate Structural

What is Cefoselis sulfate?

Description

Cefoselis is a new fourth-generation cephalosporin and was launched in Japan as a parenteral antibiotic for a variety of infections including Staphylococcus aureus (particularly the methicillin-resistant MRSA) and Pseudornonas aeruginosa. It can be prepared in 3 related ways, all using 2- pyrazolomethyl-3-cephem-4-carboxylic as the key intermediate. In preclinical studies, Cefolesis had better MIC50s than Ceftazidime against Streptococcus pneurnoniae or Staphflococcus aureus (methicillin-sensitive MSSA or resistant MRSA) and showed significant antibacterial activity against Citrobacter and Enterobacter.
Cefolesis is well tolerated in clinical studies, being eliminated mainly via glomerular filtration in humans.

Originator

Fujisawa (Japan)

The Uses of Cefoselis sulfate

antibiotic

Definition

ChEBI: Cefoselis sulfate is an azaheterocycle sulfate salt. It is functionally related to a member of cefoselis.

brand name

Wincef

Properties of Cefoselis sulfate

storage temp.  4°C, protect from light, stored under nitrogen
solubility  DMSO : 100 mg/mL (161.12 mM; Need ultrasonic)H2O : 14.29 mg/mL (23.02 mM; Need ultrasonic)
form  Powder
color  White to off-white
CAS DataBase Reference 122841-12-7(CAS DataBase Reference)

Safety information for Cefoselis sulfate

Computed Descriptors for Cefoselis sulfate

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