Cefoselis sulfate
- CAS NO.：122841-12-7
- Empirical Formula: C19H24N8O10S3
- Molecular Weight: 620.63
- MDL number: MFCD01940015
- EINECS: 1533716-785-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is Cefoselis sulfate?
Description
Cefoselis is a new fourth-generation cephalosporin and was launched
in Japan as a parenteral antibiotic for a variety of infections including
Staphylococcus aureus (particularly the methicillin-resistant MRSA) and
Pseudornonas aeruginosa. It can be prepared in 3 related ways, all using 2-
pyrazolomethyl-3-cephem-4-carboxylic as the key intermediate. In preclinical
studies, Cefolesis had better MIC50s than Ceftazidime against Streptococcus
pneurnoniae or Staphflococcus aureus (methicillin-sensitive MSSA or resistant
MRSA) and showed significant antibacterial activity against Citrobacter and
Enterobacter.
Cefolesis is well tolerated in clinical studies, being eliminated mainly via
glomerular filtration in humans.
Originator
Fujisawa (Japan)
The Uses of Cefoselis sulfate
antibiotic
Definition
ChEBI: Cefoselis sulfate is an azaheterocycle sulfate salt. It is functionally related to a member of cefoselis.
brand name
Wincef
Properties of Cefoselis sulfate
| storage temp. | 4°C, protect from light, stored under nitrogen |
| solubility | DMSO : 100 mg/mL (161.12 mM; Need ultrasonic)H2O : 14.29 mg/mL (23.02 mM; Need ultrasonic) |
| form | Powder |
| color | White to off-white |
| CAS DataBase Reference | 122841-12-7(CAS DataBase Reference) |
Safety information for Cefoselis sulfate
Computed Descriptors for Cefoselis sulfate
New Products
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