CARBONIC ACID DI-2-PYRIDYL ESTER
- CAS NO.:1659-31-0
- Empirical Formula: C11H8N2O3
- Molecular Weight: 216.19
- MDL number: MFCD00191407
- EINECS: 213-988-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 15:15:27
What is CARBONIC ACID DI-2-PYRIDYL ESTER?
Chemical properties
White to faint yellow crystalline powder
The Uses of CARBONIC ACID DI-2-PYRIDYL ESTER
Di-2-pyridyl carbonate is used as a coupling agent in the esterification of carboxylic acids (e.g. 3-Cyclohexenylcarboxylic acid [C988195]). Di-2-pyridyl carbonate is also used as a reagent to synthesize active carbonates (e.g. benzyl 2-pyridyl carbonate) and carbamates (e.g. 3-Pyridyl diethylcarbamate [P992950]).
Preparation
A solution of phosgene (2.5 m in toluene, 2 mL, 5.0 mmol) was diluted with dichloromethane (8 mL) and then a solution of 2-pyridinol 853 (950 mg, 10 mmol) and triethylamine (1.214 g, 10.2 mmol) in dichloromethane (20 mL) was added at 0 ℃. The reaction mixture was stirred at 0℃ for 1 h, then washed with cold 5% NaHCO3 solution (20 mL) and cold saturated brine (20 mL), dried over MgSO4, and filtered. The filtrate was concentrated to dryness to give di-2-pyridyl carbonate, DPC, 725 (972 mg) in 90% yield. It was recrystallized from dichloromethane/petroleum ether (811 mg, 75%); mp 84–86℃. DPC has also been produced as its hydrochloride salt 877, in a more facile procedure on a larger scale, in 97% yield.
Properties of CARBONIC ACID DI-2-PYRIDYL ESTER
Melting point: | 90 °C |
Boiling point: | 351.6±17.0 °C(Predicted) |
Density | 1.307 |
Flash point: | 166.438℃ |
storage temp. | Inert atmosphere,2-8°C |
form | powder to crystal |
pka | 0.63±0.12(Predicted) |
color | White to Light yellow |
CAS DataBase Reference | 1659-31-0(CAS DataBase Reference) |
Safety information for CARBONIC ACID DI-2-PYRIDYL ESTER
Computed Descriptors for CARBONIC ACID DI-2-PYRIDYL ESTER
InChIKey | GCSAXWHQFYOIFE-UHFFFAOYSA-N |
New Products
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