Tetraethylene glycol di-p-tosylate

Synonym(s):Tetraethylene glycol ditosylate

CAS NO.：37860-51-8
Empirical Formula: C22H30O9S2
Molecular Weight: 502.6
MDL number: MFCD00075239
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-17 10:44:43

Tetraethylene glycol di-p-tosylate Structural

What is Tetraethylene glycol di-p-tosylate?

Description

Tos-PEG5-Tos is a PEG linker containing two tosyl groups. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

The Uses of Tetraethylene glycol di-p-tosylate

Tetraethylene glycol di(p-toluenesulfonate) was used in the preparation of donor-spacer-acceptor podand system, dual channel fluorosensor for Li⁺, Mg²⁺ and Ca²⁺.

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year;

Properties of Tetraethylene glycol di-p-tosylate

Melting point:	65-69 °C
Boiling point:	635.0±55.0 °C(Predicted)
Density	1.242 g/mL at 25 °C (lit.)
refractive index	n20/D 1.53(lit.)
Flash point:	>230 °F
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
color	colorless to yellow
BRN	1610992
InChI	InChI=1S/C22H30O9S2/c1-19-3-7-21(8-4-19)32(23,24)30-17-15-28-13-11-27-12-14-29-16-18-31-33(25,26)22-9-5-20(2)6-10-22/h3-10H,11-18H2,1-2H3
EPA Substance Registry System	Ethanol, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-, bis(4-methylbenzenesulfonate) (37860-51-8)

Safety information for Tetraethylene glycol di-p-tosylate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.