Carbobenzoxyhydrazide
Synonym(s):(Benzyloxycarbonyl)hydrazine;Z-hydrazine
- CAS NO.：5331-43-1
- Empirical Formula: C8H10N2O2
- Molecular Weight: 166.18
- MDL number: MFCD00041890
- EINECS: 226-230-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-29 11:48:30
What is Carbobenzoxyhydrazide?
Chemical properties
LIGHT BEIGE SHINY FLAKES
The Uses of Carbobenzoxyhydrazide
Benzyl Carbazate has been shown to prevent the occurrence of oligonucleosome-sized DNA fragmentation in the cell-free system.
The Uses of Carbobenzoxyhydrazide
Benzyl carbazate is used as a reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method. It is also used in the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation.
Properties of Carbobenzoxyhydrazide
| Melting point: | 65-68 °C (lit.) |
| Boiling point: | 294.38°C (rough estimate) |
| Density | 1.2265 (rough estimate) |
| refractive index | 1.6180 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO, Methanol |
| pka | 10.56±0.20(Predicted) |
| form | Solid |
| color | Beige |
| Water Solubility | Soluble in water (slightly), methanol and DMSO. |
| BRN | 1952982 |
| CAS DataBase Reference | 5331-43-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Hydrazinecarboxylic acid, phenylmethyl ester(5331-43-1) |
| EPA Substance Registry System | Hydrazinecarboxylic acid, phenylmethyl ester (5331-43-1) |
Safety information for Carbobenzoxyhydrazide
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Carbobenzoxyhydrazide
| InChIKey | RXUBZLMIGSAPEJ-UHFFFAOYSA-N |
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