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HomeProduct name listtert-Butyl carbazate

tert-Butyl carbazate

Synonym(s):tert-Butoxycarbonyl hydrazide;tert-Butyl hydrazinecarboxylate;Boc-hydrazide

  • CAS NO.:870-46-2
  • Empirical Formula: C5H12N2O2
  • Molecular Weight: 132.16
  • MDL number: MFCD00007593
  • EINECS: 212-795-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-05-13 18:00:15
tert-Butyl carbazate Structural

What is tert-Butyl carbazate?

The Uses of tert-Butyl carbazate

tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

Properties of tert-Butyl carbazate

Melting point: 39-42 °C (lit.)
Boiling point: 63-65 °C/0.1 mmHg (lit.)
Density  1.02
Flash point: 197 °F
storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility  Soluble in ethanol and methanol.
form  Crystalline Lumps
color  White to slightly yellow
Sensitive  Moisture Sensitive

Safety information for tert-Butyl carbazate

Signal word Danger
Pictogram(s)

Flame
Flammables
GHS02
GHS Hazard Statements H228:Flammable solids
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

Computed Descriptors for tert-Butyl carbazate

InChIKey DKACXUFSLUYRFU-UHFFFAOYSA-N

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