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HomeProduct name listCARBETAPENTANE CITRATE

CARBETAPENTANE CITRATE

  • CAS NO.:23142-01-0
  • Empirical Formula: C26H39NO10
  • Molecular Weight: 525.59
  • MDL number: MFCD00055697
  • EINECS: 245-449-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-30 18:52:02
CARBETAPENTANE CITRATE Structural

What is CARBETAPENTANE CITRATE?

Chemical properties

White to Off-White Solid

Originator

Asthma ,Nichiiko

The Uses of CARBETAPENTANE CITRATE

An over-the-counter cough suppressant.

The Uses of CARBETAPENTANE CITRATE

antibacterial, antiproliferative

The Uses of CARBETAPENTANE CITRATE

Sigma receptor agonist

What are the applications of Application

Carbetapentane citrate is a compound shown to increase effectiveness of diphenylhydantoin

Definition

ChEBI: Carbetapentane citrate is a carbonyl compound.

Manufacturing Process

1-Phenylcyclopentane carbonitrile was obtained by treatment of phenylacetonitrile with sodium amide and 1,4-dibrombutane.
1-Phenyl-1-cyclopentane carboxylic acid was produced in the result of reaction of 1-phenylcyclopentane carbonitrile with sulfuric acid.
1-Phenyl-1-cyclopentanecarbonyl chloride was obtained by treatment of 1phenyl-1-cyclopentane carboxylic acid with thionyl chloride.
A mixture of 0.5 mol of 1-phenyl-1-cyclopentanecarbonyl chloride and of 0.5 mol of 2-(2-diethylaminoethoxy)ethanol (herein-after referred to as the amino alcohol) in 300 ml of toluene is heated under reflux for 20 h. The mixture is thereafter made alkaline by means of an aqueous solution of caustic soda and decanted; the toluenic layer is washed with water and concentrated in vacuo. The residue is distilled under high vacuum. After two fractional distillations, the 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane-carboxylate is obtained, in 85% yield. Boiling point 164°C/0.1 mm. Hg.

brand name

Toclase (Pfizer).

Therapeutic Function

Antitussive

Biological Activity

A selective ligand for the σ 1 -site.

Properties of CARBETAPENTANE CITRATE

Melting point: 84-86?C
storage temp.  Sealed in dry,2-8°C
solubility  H2O: soluble
form  Solid
color  White to Off-White

Safety information for CARBETAPENTANE CITRATE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H312:Acute toxicity,dermal
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H332:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for CARBETAPENTANE CITRATE

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