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HomeProduct name listbucumolol hydrochloride

bucumolol hydrochloride

bucumolol hydrochloride Structural

What is bucumolol hydrochloride?

Originator

Bucumarol,Sankyo,Japan,1982

Definition

ChEBI: Bucumolol hydrochloride is a member of coumarins.

Manufacturing Process

A mixture of 3 g of 8-(2-hydroxy-3-chloropropoxy)-5-methyl coumarin, 4.3 g of t-butylamine and 60 ml of ethanol is heated at 100°C in a sealed tube for 15 hours. The reaction mixture is concentrated under reduced pressure to dryness. The residue is recrystallized from a mixture of ethanol and ether to give 2.1 g of the desired product melting at 226° to 228°C (with decomposition).
In practice it is usually used as hydrochloride.

Therapeutic Function

Beta-adrenergic blocker

Properties of bucumolol hydrochloride

Melting point: 226-228° (dec)

Safety information for bucumolol hydrochloride

Computed Descriptors for bucumolol hydrochloride

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