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HomeProduct name listtert-Butoxy bis(dimethylamino)methane

tert-Butoxy bis(dimethylamino)methane

Synonym(s):Bredereck’s reagent

  • CAS NO.:5815-08-7
  • Empirical Formula: C9H22N2O
  • Molecular Weight: 174.28
  • MDL number: MFCD00042858
  • EINECS: 227-383-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-22 11:38:30
tert-Butoxy bis(dimethylamino)methane Structural

What is tert-Butoxy bis(dimethylamino)methane?

Chemical properties

Clear pale yellow liquid

The Uses of tert-Butoxy bis(dimethylamino)methane

Reactant for:• ;Preparation of pyrroloquinazolines as photochemotherapeutic agents1• ;Enanatioslective formal synthesis of the Cinchona alkaloid quinine via stereoselective intermolecular radical addition2• ;Synthesis of camptothecin via intramolecular isomuenchnone cycloaddition reaction3• ;Aminomethylenation reactions4

The Uses of tert-Butoxy bis(dimethylamino)methane

Mild enamination reagent; catalyst in ring-opening polymerization reactions.

The Uses of tert-Butoxy bis(dimethylamino)methane

Reactant for:

  • Preparation of pyrroloquinazolines as photochemotherapeutic agents
  • Enanatioslective formal synthesis of the Cinchona alkaloid quinine via stereoselective intermolecular radical addition
  • Synthesis of camptothecin via intramolecular isomuenchnone cycloaddition reaction
  • Aminomethylenation reactions

Properties of tert-Butoxy bis(dimethylamino)methane

Boiling point: 50-55 °C/15 mmHg (lit.)
Density  0.844 g/mL at 25 °C (lit.)
refractive index  n20/D 1.422(lit.)
Flash point: 106 °F
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
pka 5.46±0.38(Predicted)
form  Liquid
color  Clear pale yellow
Specific Gravity 0.844
BRN  1901973
Stability: Hygroscopic
InChI InChI=1S/C9H22N2O/c1-9(2,3)12-8(10(4)5)11(6)7/h8H,1-7H3
CAS DataBase Reference 5815-08-7(CAS DataBase Reference)

Safety information for tert-Butoxy bis(dimethylamino)methane

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for tert-Butoxy bis(dimethylamino)methane

InChIKey HXRAMSFGUAOAJR-UHFFFAOYSA-N
SMILES C(OC(C)(C)C)(N(C)C)N(C)C

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