BOC-LYS(AC)-AMC
Synonym(s):Boc-Lys(Ac)-AMC, MAL, N-(4-Methyl-7-coumarinyl)-N α-(t-butoxycarbonyl)-N ω-acetyllysinamide;Histone Deacetylase Substrate, Fluorogenic - CAS 233691-67-3 - Calbiochem
- CAS NO.：233691-67-3
- Empirical Formula: C23H31N3O6
- Molecular Weight: 445.51
- MDL number: MFCD02683946
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-13 11:39:26
What is BOC-LYS(AC)-AMC?
Description
Boc-Lys(Ac)-AMC is a fluorescent substrate for histone deacetylases (HDACs). Following deacetylation by an HDAC, Boc-Lys-AMC is cleaved by trypsin and 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify HDAC activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Properties of BOC-LYS(AC)-AMC
| Boiling point: | 732.6±60.0 °C(Predicted) |
| Density | 1.209±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml |
| form | White crystalline solid |
| pka | 11.23±0.46(Predicted) |
| color | White to off-white |
Safety information for BOC-LYS(AC)-AMC
Computed Descriptors for BOC-LYS(AC)-AMC
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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