BIOTIN-XX-NHS
Synonym(s):6-(Biotinamidocaproylamido)caproic acid N-hydroxysuccinimide ester;Biotin-X-X-NHS;N-Succinimidyl N-[6-(biotinylamino)caproyl]-6-aminocaproate
- CAS NO.：89889-52-1
- Empirical Formula: C26H41N5O7S
- Molecular Weight: 567.7
- MDL number: MFCD00467154
- EINECS: 205-525-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-07 21:39:59
What is BIOTIN-XX-NHS?
Description
Biotin-LC-LC-NHS is a biotinylation reagent that contains an N-hydroxysuccinimide (NHS) moiety, which activates carboxylic acid groups on biotin to facilitate coupling reactions, and a 30.5 Å spacer to decrease steric hindrance. It has been used to biotinylate small molecules such as paclitaxel and coenzyme Q10 for use in binding site characterization.
Chemical properties
White Solid
The Uses of BIOTIN-XX-NHS
A biotinylated cross-linking reagent.
The Uses of BIOTIN-XX-NHS
trifunctional aziridine reagent very reactive for active hydrogen groups
The Uses of BIOTIN-XX-NHS
Biotinamidohexanoyl-6-aminohexanoic acid N-hydroxysuccinimide ester has been used in human IgM biotinylation.
Properties of BIOTIN-XX-NHS
| Melting point: | 147-151°C |
| Density | 1.29±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMF: 25 mg/mL |
| form | powder |
| pka | 13.90±0.40(Predicted) |
| color | White to Almost white |
| BRN | 8377428 |
| Stability: | Moisture Sensitive |
| CAS DataBase Reference | 89889-52-1 |
Safety information for BIOTIN-XX-NHS
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for BIOTIN-XX-NHS
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