Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listBIOTIN-NHS

BIOTIN-NHS

Synonym(s):Biotin-NHS;NHS-Biotin;Biotin-OSu;BNHS;N-(Biotinyloxy)succinimide

  • CAS NO.:35013-72-0
  • Empirical Formula: C14H19N3O5S
  • Molecular Weight: 341.38
  • MDL number: MFCD00078531
  • EINECS: 609-055-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-23 13:36:13
BIOTIN-NHS Structural

What is BIOTIN-NHS?

Description

N-Hydroxysuccinimide (NHS) activates carboxylic acid groups (on biotin) to facilitate coupling reactions. Biotin-NHS is a compound used to attach biotin to primary amines under alkaline conditions (pH~8-9). For example, lysines on the surface of proteins, including antibodies, are ideal targets for biotinylation with this compound.

Chemical properties

White Solid

The Uses of BIOTIN-NHS

amine reactive biotinylation reagent

The Uses of BIOTIN-NHS

Biotin-NHS is used in the biotinylation of proteins and peptides. Couples with primary amine in the pH range 6.5-8.5.

The Uses of BIOTIN-NHS

Amino reactive biotin reagent for preparing biotinylated surfaces or polypeptides.

Purification Methods

Recrystallise the ester from refluxing isoPrOH and dry it in a vacuum over P2O5 + KOH. [Jasiewicz et al. Exp Cell Biol 100 213 1976.]

Properties of BIOTIN-NHS

Melting point: 212-214 °C
Density  1.45±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMF: ≤50 mg/mL Stable for at least one month in dry DMF
form  powder
pka 13.89±0.40(Predicted)
color  White to off-white
BRN  4720781
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 35013-72-0(CAS DataBase Reference)

Safety information for BIOTIN-NHS

Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for BIOTIN-NHS

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.