BETA-NAADP SODIUM SALT
Synonym(s):β-NAADP
- CAS NO.：5502-96-5
- Empirical Formula: C21H28N7O17P3
- Molecular Weight: 743.41
- MDL number: MFCD00274064
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:01
What is BETA-NAADP SODIUM SALT?
The Uses of BETA-NAADP SODIUM SALT
NAADP Tetrasodium Salt is a Ca2+ mobilizing agent.
The Uses of BETA-NAADP SODIUM SALT
Nicotinic acid adenine dinucleotide phosphate sodium salt has been used for agonist injection into unfertilized eggs and embryos.
What are the applications of Application
Nicotinic acid adenine dinucleotide phosphate sodium salt is a potent activator of intracellular Ca2+ mobilzation
General Description
NAADP induces Ca2+?release from the eggs of sea urchin, when injected into the cell. It can be enzymatically produced from nicotinamide adenine dinucleotide phosphate (β-NADP) with the help of ADP-ribosyl cyclase.
Biological Activity
Ca 2+ mobilizing agent. Initiates Ca 2+ release via type 1 ryanodine receptor (RyR1) activation. Also regulates Ca 2+ release from intracellular stores distinct from the endoplasmic reticulum (ER); displays affinity for two-pore channels (TPCs) which release Ca 2+ from acidic organelles.
Biochem/physiol Actions
Potent activator of intracellular Ca2+ release via an IP3 and cyclic ADP ribose-independent mechanism.
Properties of BETA-NAADP SODIUM SALT
| storage temp. | -20°C |
| form | Powder |
| color | White to off-white |
| Water Solubility | Soluble to 50 mM in water |
Safety information for BETA-NAADP SODIUM SALT
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for BETA-NAADP SODIUM SALT
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