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HomeProduct name listBenzyltrimethylammonium hydroxide

Benzyltrimethylammonium hydroxide

  • CAS NO.:100-85-6
  • Empirical Formula: C10H17NO
  • Molecular Weight: 167.25
  • MDL number: MFCD00008281
  • EINECS: 202-895-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-24 19:19:26
Benzyltrimethylammonium hydroxide Structural

What is Benzyltrimethylammonium hydroxide?

Chemical properties

CLEAR SLIGHTLY YELLOW SOLUTION

The Uses of Benzyltrimethylammonium hydroxide

Benzyltrimethylammonium hydroxide is used as a phase-transfer catalyst. It is also used in aldol condensation reactions and base-catalyzed dehydration reactions. Further, it serves as a strong organic base and used in Horner-Wadsworth-Emmons olefination reactions. In addition, it is an active component in the formulation, which is used in silicon wafer cleaning applications.

The Uses of Benzyltrimethylammonium hydroxide

Benzyltrimethylammonium hydroxide can be used:

  • As a base in the synthesis of activated ynesulfonamides and tertiary enesulfonamides.
  • In the synthesis of 3-indolyl-3-hydroxy oxindoles by treating isatin with indole.
  • As a precursor for the preparation of quaternary ammonium acetate, benzyltrimethylammonium acetate (NBz111AcO). NBz111AcO solution in DMSO can be used to dissolve cellulose.

What are the applications of Application

Benzyltrimethylammonium Hydroxide (40% in Water) is a quaternary ammonium salt that functions as an organic base

Flammability and Explosibility

Not classified

Safety Profile

Poison by subcutaneous route. Astrong base. When heated to decomposition it emits toxicfumes of NH3 and NOx.

Purification Methods

A 38% solution (as supplied) is decolorized (charcoal), then evaporated under reduced pressure to a syrup, with final drying at 75o/1mm pressure. The anhydrous base is obtained by prolonged drying over P2O5 in a vacuum desiccator. [Beilstein 12 IV 2162.]

Properties of Benzyltrimethylammonium hydroxide

Melting point: 80 °C
Boiling point: 65°C
Density  1.059 g/mL at 25 °C
vapor pressure  0Pa at 25℃
refractive index  n20/D 1.43
Flash point: 60 °F
storage temp.  Store below +30°C.
solubility  Miscible with alcohols, hydrocarbons, aromatic hydrocarbons and halogenated solvents.
form  Solution
color  Clear slightly yellow
explosive limit 5.50-36.50%
Water Solubility  Miscible with water, hydrocarbons, aromatic hydrocarbons and halogenated solvents.
Sensitive  Air Sensitive
BRN  3917256
Exposure limits ACGIH: TWA 200 ppm; STEL 250 ppm (Skin)
OSHA: TWA 200 ppm(260 mg/m3)
NIOSH: IDLH 6000 ppm; TWA 200 ppm(260 mg/m3); STEL 250 ppm(325 mg/m3)
CAS DataBase Reference 100-85-6(CAS DataBase Reference)
EPA Substance Registry System Benzyltrimethylammonium hydroxide (100-85-6)

Safety information for Benzyltrimethylammonium hydroxide

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Corrosion
Corrosives
GHS05
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
GHS Hazard Statements H225:Flammable liquids
H314:Skin corrosion/irritation
H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Benzyltrimethylammonium hydroxide

InChIKey NDKBVBUGCNGSJJ-UHFFFAOYSA-M

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