BANISTERINE MONOHYDRATE
Synonym(s):7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole
- CAS NO.：442-51-3
- Empirical Formula: C13H12N2O
- Molecular Weight: 212.25
- MDL number: MFCD00150055
- EINECS: 207-131-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-06 18:33:45
What is BANISTERINE MONOHYDRATE?
Chemical properties
Off-White Solid
The Uses of BANISTERINE MONOHYDRATE
antiparkinsonian, CNS stimulant
The Uses of BANISTERINE MONOHYDRATE
central nervous system stimulant
The Uses of BANISTERINE MONOHYDRATE
A CNS stimulant isolated from seeds of Peganum harmala L. Zygophyllaceae
What are the applications of Application
Harmine is an alkaloid of the β-carboline family that regulates PPARγ expression.
Definition
ChEBI: A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7.
General Description
The combination index (CI, serves as a quantitative indicator of pharmacological interactions) for harmaline/harmine and methylene blue/harmine was studied.
storage
Store at RT
Purification Methods
Crystallise harmine from MeOH and sublime it in a vacuum. See hydrochloride below. [Beilstein 23 II 348, 23 III/IV 2702, 23/12 V 237.]
Properties of BANISTERINE MONOHYDRATE
| Melting point: | 262-264 °C(lit.) |
| Boiling point: | 352.09°C (rough estimate) |
| Density | 1.1128 (rough estimate) |
| refractive index | 1.6920 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Solubility Slightly soluble in water, ethanol, ether, chloroform |
| pka | 7.7(at 25℃) |
| form | Crystalline Powder |
| color | White to off-white |
| PH Range | Blue 0 uorescence (7.2) to yellow 0 uorescence (8.9) |
| Water Solubility | Soluble in DMSO (100 mM), DMF (~1.5 mg/ml), ethanol (~1.5 mg/ml), and PBS (pH 7.2, ~0.25 mg/ml). Insoluble in water. |
| λmax | 241nm, 301nm, 336nm |
| Merck | 14,4616 |
| BRN | 178813 |
| Major Application | Inks, antitumor agents, inhibition of cell proliferation, blocking breast and prostate cancer cells, tracer for ductal pancreatic cancer, DNA binding properties, treatment of neoplasia, antioxidants, therapy of depression, antileishmanial agent, treatment of parkinsonism, antiAIDS agents, antihypoxia agents, drugs, treatment of dependency disorder, psychiatric and neurological illness, antibiotics, antimalarial agents |
| CAS DataBase Reference | 442-51-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Harmine(442-51-3) |
Safety information for BANISTERINE MONOHYDRATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for BANISTERINE MONOHYDRATE
| InChIKey | BXNJHAXVSOCGBA-UHFFFAOYSA-N |
BANISTERINE MONOHYDRATE manufacturer
AVIGYABIOSCIENCES PRIVATE LIMITED
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Phone:+919849533087
Whatsapp: +91-9849533087
product: Harmine 98%
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