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HomeProduct name listBalsalazide disodium

Balsalazide disodium

  • CAS NO.:150399-21-6
  • Empirical Formula: C17H18N3NaO7
  • Molecular Weight: 399.33
  • MDL number: MFCD01631117
  • EINECS: 1533716-785-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-09-20 16:43:00
Balsalazide disodium Structural

What is Balsalazide disodium?

The Uses of Balsalazide disodium

Balsalazide Disodium Dihydrate is an analogue of Sulfasalazine (S699084), A prodrug of 5-aminosalicylic acid where carrier molecule is 4-aminobenzoyl-β-alanine. Anti-inflammatory (gastrointestinal).

The Uses of Balsalazide disodium

antiinflammatory

definition

ChEBI: The dihydrate of the disodium salt of balsalazide. A prodrug, releasing the anti-inflammatory 5-aminosalicylic acid (mesalazine) in the large intestine, it is used in the treatment of ulcerative colitis.

Indications

Balsalazide disodium is delivered intact to the colon, where it is cleaved by bacterial azoreduction to release equimolar quantities of mesalamine, the therapeutically active portion of the molecule, and 4-aminobenzoyl-β-alanine; the latter compound is only minimally absorbed and is largely inert.

brand name

Colazal (Salix).

Properties of Balsalazide disodium

Melting point: >195°C (dec.)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form  Solid
color  Yellow
Merck  14,945

Safety information for Balsalazide disodium

Computed Descriptors for Balsalazide disodium

InChIKey XDCNKOBSQURQOZ-MVIJUDHYSA-L

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