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HomeProduct name listArjunolic acid

Arjunolic acid

Synonym(s):2,3,23-Trihydroxyolean-12-en-28-oic acid

Arjunolic acid Structural

What is Arjunolic acid?

Description

Arjunolic acid is a triterpene that has been found in T. arjuna and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay when used at a concentration of 0.8 mM. Arjunolic acid (20 mg/kg for four days) prevents arsenic-induced decreases in the activity of superoxide dismutase (SOD1), catalase, GST, and glutathione reductase in mouse brain. It reduces tumor growth in an Ehrlich murine spontaneous adenocarcinoma model when administered at doses of 100 and 250 mg/kg for 20 days. Arjunolic acid reduces renal fibrosis and increases in kidney TNF-α and IL-1β levels induced by cisplatin in mice when administered at doses of 100 and 250 mg/kg per day for 10 days.

The Uses of Arjunolic acid

Arjunolic Acid is a naturally occurring terpenoid which displays anti-inflammatory activity as well as protective effects during chemical induced organ pathophysiology.

What are the applications of Application

Arjunolic acid is a pentacyclic triterpenoid

Definition

ChEBI: A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). Isolated from Symplocos lancifolia and Juglans sinensi , it exhibits antioxidant and antimicrobial activities.

Properties of Arjunolic acid

Melting point: 332-334 °C
Boiling point: 606.0±55.0 °C(Predicted)
Density  1.19±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Powder
pka 4.62±0.70(Predicted)
color  White to off-white

Safety information for Arjunolic acid

Computed Descriptors for Arjunolic acid

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