ARA-S
- CAS NO.:187224-29-9
- Empirical Formula: C23H37NO4
- Molecular Weight: 391.54
- MDL number: MFCD08062151
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-14 17:47:39
What is ARA-S?
Description
Arachidonoyl amides of both amino acids and neurotransmitters such as dopamine have been previously reported in the literature. N-
The Uses of ARA-S
N-Arachidonoyl-L-serine is a novel neuroprotective endocannabinoid with weak affinity for CB1 and CB2 cannabinoid receptors. It is also a pro-angiogenic factor and a vessel dilator. Shows proneurogenic properties in vitro and invivo in mice model of traumatic brain injury. (1) Exhibits neuroprotection via ERK and Akt phosphorylation and induction of their downstream antiapoptotic pathways (2)
What are the applications of Application
N-Arachidonoyl-L-serine is an endocannabinoid-like compound and CB1/CB2 agonist
Definition
ChEBI: N-arachidonoyl-L-serine is an N-acyl-amino acid resulting from the formal condensation of the carboxy group of arachidonic acid with the amino group of L-serine. It is an endocannabinoid-like lipid isolated from bovine brains. It has a role as a cannabinoid receptor agonist, a vasodilator agent, a pro-angiogenic agent, a neuroprotective agent and a mammalian metabolite. It is functionally related to an arachidonic acid and a L-serine. It is a conjugate acid of a N-arachidonoyl-L-serine(1-).
Properties of ARA-S
Boiling point: | 607.6±55.0 °C(Predicted) |
Density | 1.027±0.06 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 2 mg/ml |
pka | 3.26±0.10(Predicted) |
Safety information for ARA-S
Computed Descriptors for ARA-S
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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