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HomeProduct name listAMINOGUANIDINE HEMISULFATE

AMINOGUANIDINE HEMISULFATE

Synonym(s):1-Aminoguanidinium sulfate;Bis(1-aminoguanidinium) sulfate;Guanylhydrazine hemisulfate salt

  • CAS NO.:996-19-0
  • Empirical Formula: CH8N4O4S
  • Molecular Weight: 172.16
  • MDL number: MFCD00035665
  • EINECS: 213-628-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 23:16:16
AMINOGUANIDINE HEMISULFATE Structural

What is AMINOGUANIDINE HEMISULFATE?

Chemical properties

WHITE CRYSTALS OR CRYSTALLINE POWDER

The Uses of AMINOGUANIDINE HEMISULFATE

NO synthase inhibitor

The Uses of AMINOGUANIDINE HEMISULFATE

Aminoguanidine inhibits both constitutive and inducible nitric oxide synthetase. Aminoguanidine has also been used to study the effects of nitric oxide on ovulation and ovarian steroidogenesis and prostaglandin production.

What are the applications of Application

Aminoguanidine hemisulfate is a NOS (nitric oxide synthase) inhibitor

What are the applications of Application

Aminoguanidine hemisulfate is used in the treatment of patients with chronic granulomatous disease, which is a form of leukemia. This drug also has been shown to inhibit follicular growth and nitrogen atoms, as well as to inhibit the production of protein-bound polyamines. It was found to have no effect on the intracellular calcium concentration or on growth factor release by receptor cells. It has been shown that it can inhibit cyclase activity and therefore reduce proliferation of cells in experimental models. The ester hydrochloride salt of this compound is an inhibitor of guanylate cyclase, which prevents the conversion of guanosine triphosphate (GTP) into cyclic guanosine monophosphate (cGMP).

Biochem/physiol Actions

Inhibits both constitutive and inducible nitric oxide synthetase

Properties of AMINOGUANIDINE HEMISULFATE

Melting point: 200 °C
Density  1.36 g/cm3 (20℃)
storage temp.  Store below +30°C.
solubility  170g/l
form  White solid.
color  White to Almost white
PH 4-6 (25g/l, H2O, 20℃)
Water Solubility  almost transparency
CAS DataBase Reference 996-19-0(CAS DataBase Reference)
EPA Substance Registry System Hydrazinecarboximidamide, sulfate (2:1) (996-19-0)

Safety information for AMINOGUANIDINE HEMISULFATE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H227:Flammable liquids
H315:Skin corrosion/irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P362:Take off contaminated clothing and wash before reuse.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P370+P378:In case of fire: Use … for extinction.
P403+P235:Store in a well-ventilated place. Keep cool.
P501:Dispose of contents/container to..…

Computed Descriptors for AMINOGUANIDINE HEMISULFATE

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