Aminoguanidine bicarbonate
Synonym(s):1-Aminoguanidinium hydrogen carbonate;Aminoguanidine bicarbonate;Aminoguanidine hydrogencarbonate;Guanylhydrazine hydrogencarbonate
- CAS NO.:2582-30-1
- Empirical Formula: C2H8N4O3
- Molecular Weight: 136.11
- MDL number: MFCD00012949
- EINECS: 219-956-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is Aminoguanidine bicarbonate?
Chemical properties
White to off-white crystalline powder. It is almost insoluble in water, alcohol and other acids.
The Uses of Aminoguanidine bicarbonate
Aminoguanidine bicarbonate (AGB) is of practical importance because of its use in dyes, dispersants, explosives and other commercial applications. It is used in the synthesis of antitumor agents and antileukemic activity. Also used in the synthesis of neuraminidase inhibitors in the inhibition of influenze.
What are the applications of Application
Aminoguanidine bicarbonate is an inhibitor of NOS (nitric oxide synthase). Aminoguanidine bicarbonate is used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5.
Biochem/physiol Actions
Aminoguanidine bicarbonate protects the cells infected with adenovirus from chromosomal damage. Aminoguanidine is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum.
Synthesis
A synthesis method of aminoguanidine bicarbonate includes reacting an acidic aqueous hydrazine hydrate solution with calcium cyanamide in an elevated temperature to produce an aminoguanidine solution, recovering the solution, and reacting therewith an alkali metal bicarbonate to produce relatively high purity aminoguanidine bicarbonate.
storage
+4°C
Properties of Aminoguanidine bicarbonate
Melting point: | 170-172 °C (dec.)(lit.) |
Density | 1,6 g/cm3 |
storage temp. | Store below +30°C. |
solubility | H2O: soluble2.7g/L at 20°C |
form | Crystalline Powder |
pka | 6.19[at 20 ℃] |
color | White to off-white |
PH | 8.9 (5g/l, H2O, 20℃) |
Water Solubility | <5 g/L (20 ºC) |
BRN | 3569869 |
CAS DataBase Reference | 2582-30-1(CAS DataBase Reference) |
EPA Substance Registry System | Carbonic acid, compd. with hydrazinecarboximidamide (1:1) (2582-30-1) |
Safety information for Aminoguanidine bicarbonate
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Environment GHS09 |
GHS Hazard Statements |
H317:Sensitisation, Skin H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Aminoguanidine bicarbonate
InChIKey | OTXHZHQQWQTQMW-UHFFFAOYSA-N |
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