Amino-PEG1-t-Butyl ester

CAS NO.：1260092-46-3
Empirical Formula: C9H19NO3
Molecular Weight: 189.25
MDL number: MFCD20727480
Update Date: 2024-10-23 13:36:13

What is Amino-PEG1-t-Butyl ester?

Description

Amino-PEG1-t-butyl ester is a PEG reagent containing an amino group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-Boc group can be deprotected under acidic conditions.

The Uses of Amino-PEG1-t-Butyl ester

Amino-peg1-t-butyl Ester is a reagent used in the preparation of β2 adrenergic receptor agonists and muscarinic receptor activity antagonists.

Properties of Amino-PEG1-t-Butyl ester

Boiling point:	264.9±15.0 °C(Predicted)
Density	0.992±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Oil
pka	8.73±0.10(Predicted)
color	Clear Colourless to Pale Yellow to Dark Yellow

Safety information for Amino-PEG1-t-Butyl ester

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.