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HomeProduct name listH2N-PEG4-tBu

H2N-PEG4-tBu

Synonym(s):tert-Butyl 1-amino-3,6,9,12-tetraoxapentadecan-15-oate;H2N-dPEG(4)-CO-OtBu;H2N-PEG4-CH2CH2COOtBu

H2N-PEG4-tBu Structural

What is H2N-PEG4-tBu?

Description

Amino-PEG4-t-butyl ester is a PEG reagent containing an amino (NH2) and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl (Boc) can be deprotected under acidic conditions.

The Uses of H2N-PEG4-tBu

is a linker-cytotoxin conjugate. Linker-cytotoxin conjugate is related to antibody-cytotoxin and antibody-drug conjugates and related compounds.

Properties of H2N-PEG4-tBu

Boiling point: 400.1±35.0 °C(Predicted)
Density  1.040±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  Soluble in Water, DMSO, DCM, DMF
pka 8.74±0.10(Predicted)
form  clear liquid
color  Colorless to Light yellow
CAS DataBase Reference 581065-95-4

Safety information for H2N-PEG4-tBu

Computed Descriptors for H2N-PEG4-tBu

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