H2N-PEG4-tBu
Synonym(s):tert-Butyl 1-amino-3,6,9,12-tetraoxapentadecan-15-oate;H2N-dPEG(4)-CO-OtBu;H2N-PEG4-CH2CH2COOtBu
- CAS NO.:581065-95-4
- Empirical Formula: C15H31NO6
- Molecular Weight: 321.41
- MDL number: MFCD11041116
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-02 10:12:10
What is H2N-PEG4-tBu?
Description
Amino-PEG4-t-butyl ester is a PEG reagent containing an amino (NH2) and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl (Boc) can be deprotected under acidic conditions.
The Uses of H2N-PEG4-tBu
is a linker-cytotoxin conjugate. Linker-cytotoxin conjugate is related to antibody-cytotoxin and antibody-drug conjugates and related compounds.
Properties of H2N-PEG4-tBu
Boiling point: | 400.1±35.0 °C(Predicted) |
Density | 1.040±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | Soluble in Water, DMSO, DCM, DMF |
pka | 8.74±0.10(Predicted) |
form | clear liquid |
color | Colorless to Light yellow |
CAS DataBase Reference | 581065-95-4 |
Safety information for H2N-PEG4-tBu
Computed Descriptors for H2N-PEG4-tBu
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
4-MALEIMIDOBUTYRIC ACID
Amino-PEG6-alcohol
5,8,11,14-Tetraoxa-2-azahexadecanoic acid,16-amino-,1,1-dimethyl ester
O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL)
HS-PEG4-tBu
2-[2-(2-methoxyethoxy)ethoxy]-ethanethiol
HO-PEG8-CH2CH2COOH
Z-8-aMino-3,6-dioxaoctanoic acid
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