Fmoc-NH-PEG8-CH2CH2COOH
Synonym(s):Fmoc-N-amido-PEG8-acid;Fmoc-N-amido-PEG8-COOH;Fmoc-NH-PEG8-acid;Fmoc-PEG-acid
- CAS NO.：756526-02-0
- Empirical Formula: C34H49NO12
- Molecular Weight: 663.75
- MDL number: MFCD11041143
- EINECS: 246-818-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-11-20 17:40:16
What is Fmoc-NH-PEG8-CH2CH2COOH?
Description
Fmoc-N-amido-PEG8-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
The Uses of Fmoc-NH-PEG8-CH2CH2COOH
Fmoc-NH-PEG8-CH2CH2COOH is used in synthesis of protein-antiviral compound conjugates.
Properties of Fmoc-NH-PEG8-CH2CH2COOH
| Boiling point: | 781.1±60.0 °C(Predicted) |
| Density | 1.190±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| pka | 4.28±0.10(Predicted) |
| color | Colorless to light yellow |
Safety information for Fmoc-NH-PEG8-CH2CH2COOH
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Fmoc-NH-PEG8-CH2CH2COOH
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