alpha-Asarone
Synonym(s):trans-1,2,4-Trimethoxy-5-(1-propenyl)benzene;trans-1-Propenyl-2,4,5-trimethoxybenzene;trans-Asarone;alpha-Asarone;Isoasaron
- CAS NO.:2883-98-9
- Empirical Formula: C12H16O3
- Molecular Weight: 208.25
- MDL number: MFCD00064457
- EINECS: 220-743-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:32
What is alpha-Asarone?
Chemical properties
Asarone is a colorless tryst. M.P. 66-67℃. B.P. 296℃. Pure Asarone is reported to be virtually odorless and tasteless. However, available samples of the material have in experiments shown perceptible influence upon the odor of compositions containing lower boiling perfume materials. Insoluble in water, soluble in alcohol and oils.
The Uses of alpha-Asarone
α-Asarone was used in the synthesis of series of α-asarone isomers and were investigated for their hypolipidemic and antiplatelet activities.
The Uses of alpha-Asarone
α-Asarone was used in the synthesis of series of α-asarone isomers and were investigated for their hypolipidemic and antiplatelet activities. It is used in the synthesis of anti-inflammatory neolignan. Also used in lignan syntheses for antiallergic agents. It is clinically used as medication for treating epilepsy, cough, bronchitis and asthma. It exhibits neuroprotective, anti-oxidative, anticonvulsive and cognitive enhancing action.
What are the applications of Application
α-Asarone is an inhibitor of HMG-CoA reductase and CYP isoenzymes
Definition
ChEBI: The trans-isomer of asarone.
What are the applications of Application
Asarone has been suggested for use as a fixative-blender with Patchouli-like odor character.
Preparation
1) by isolation from the essential oil of
Acorus Calamus.
2) synthesis. by reduction of Asaraldehyde.
General Description
Asarones are toxic morphogenetic agents. It is also known for its chemosterlant and oviposition stimulant properties. Naturally it can be extracted from Acorus calamus. α-Asarone is considered as growth inhibitor. This isomer acts as antifeedant with less toxicity.
Properties of alpha-Asarone
Melting point: | 57-61 °C(lit.) |
Boiling point: | 296 °C(lit.) |
Density | 1.1227 (rough estimate) |
refractive index | 1.5060 (estimate) |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | Soluble in chloroform, methanol. |
form | neat |
form | Solid |
color | White to Off-White |
Sensitive | Light Sensitive |
λmax | 312nm(EtOH)(lit.) |
BRN | 1910606 |
CAS DataBase Reference | 2883-98-9(CAS DataBase Reference) |
NIST Chemistry Reference | Asarone(2883-98-9) |
Safety information for alpha-Asarone
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P501:Dispose of contents/container to..… |
Computed Descriptors for alpha-Asarone
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