Aldesulfone Sodium
- CAS NO.:144-75-2
- Empirical Formula: C14H14N2Na2O6S3
- Molecular Weight: 0
- MDL number: MFCD00072004
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is Aldesulfone Sodium?
Originator
Diasone Sodium,Abbott,US,1947
The Uses of Aldesulfone Sodium
Sodium Sulfoxone is used in tuberculosis therapy along with Streptomycin (S687500).
Manufacturing Process
About 20 grams of diamino diphenyl sulfone is dissolved in about 500 cc of ethyl alcohol (3A made up of 5 parts methyl alcohol and 100 parts of ethyl alcohol) by placing the ingredients in a flask provided with a reflux condenser and warming over a water bath. About 24 grams of pure grade, very finely powdered (40 to 60 mesh) sodium formaldehyde sulfoxylate is then rapidly added to the alcohol solution of diamino diphenyl sulfone and the mixture refluxed in the usual manner. It was found that the mixture should be refluxed for a total of 5 hours and that a precipitate starts to form near the 3 hour period. The reaction mixture is then cooled to 15°C and kept at this temperature for about 1 hour. The precipitate formed in the filtrate is filtered off rapidly and drained as much as possible to remove mother liquor and then washed with small amounts of cold alcohol. The solid product is immediately placed in a desiccator and dried over sulfuric acid for about 20 hours.
Therapeutic Function
Antibacterial (leprostatic)
Properties of Aldesulfone Sodium
Melting point: | 263-265 °C (decomp) |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
color | White |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Safety information for Aldesulfone Sodium
Computed Descriptors for Aldesulfone Sodium
New Products
COBALT AAS SOLUTION HYDROXYLAMINE HYDROCHLORIDE SOLUTION 10% THOMALIT BLUE LITMUS PAPER 1 BOX SILVER NITRATE N/10 CVS GLASS BEADS 3.5 TO 4.5 MM POTASSIUM AAS SOLUTION Azithromycin Imp D Atracurium Besylate EP Impurity C Ceftaroline fosamil Acetate Hydrate Clarithromycin EP impurity F Clarithromycin EP Impurity D Clindamycin BRelated products of tetrahydrofuran
You may like
-
Atracurium Besylate EP Impurity CView Details
86293-35-8 -
Atracurium Besylate EP Impurity DView Details
87046-72-8 -
Azithromycin EP Impurity CView Details
620169-47-3 -
Azithromycin Imp DView Details
612069-26-8 -
Ceftaroline fosamil Acetate HydrateView Details
400827-55-6 -
Clarithromycin EP Impurity FView Details
128940-83-0 -
Clarithromycin EP Impurity DView Details
101666-68-6 -
Clindamycin Impurity BView Details
18323-43-8