AG 825
Synonym(s):4-Hydroxy-3-methoxy-5-(benzothiazolylthiomethyl)benzylidenecyanoacetamide;5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide;AG 825 - CAS 149092-50-2 - Calbiochem;Tyrphostin C15
- CAS NO.：149092-50-2
- Empirical Formula: C19H15N3O3S2
- Molecular Weight: 397.47
- MDL number: MFCD01074971
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is AG 825?
The Uses of AG 825
AG 825 is a selective ErbB2 (Neu) inhibitor and apoptosis inducer.
The Uses of AG 825
A selective ErbB2 inhibitor
What are the applications of Application
AG 825 is a selective ErbB2 (Neu) inhibitor and apoptosis inducer
Definition
ChEBI: An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth factor receptor antagonist.
Biological Activity
Selective ErbB2 inhibitor (IC 50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells.
storage
Store at +4°C
Properties of AG 825
| storage temp. | −20°C |
| solubility | DMSO: soluble |
| form | Yellow solid |
| color | Light yellow to yellow |
| Sensitive | Light Sensitive |
Safety information for AG 825
Computed Descriptors for AG 825
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol](https://img.chemicalbook.in/CAS/GIF/649735-46-6.gif)
You may like
-
Tyrphostin C15 CAS 149092-50-2View Details
149092-50-2 -
TYRPHOSTIN AG 825 CAS 149092-50-2View Details
149092-50-2 -
AG 825 CAS 149092-50-2View Details
149092-50-2 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 221615-75-4 98%View Details
221615-75-4 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.