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HomeProduct name listMETHYL 2,5-DIHYDROXYCINNAMATE

METHYL 2,5-DIHYDROXYCINNAMATE

METHYL 2,5-DIHYDROXYCINNAMATE Structural

What is METHYL 2,5-DIHYDROXYCINNAMATE?

Chemical properties

Yellow-Brown Crystalline Powder

The Uses of METHYL 2,5-DIHYDROXYCINNAMATE

A stable Erbstatin analogue that inhibits tyrosine kinase. Shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis

The Uses of METHYL 2,5-DIHYDROXYCINNAMATE

An inhibitor of the EGF receptor associated tyrosine kinase

What are the applications of Application

Erbstatin Analog is a stable inhibitor of EGFR tyrosine kinase

Definition

ChEBI: 2,5-dihydroxycinnamic acid methyl ester is a cinnamate ester that is the methyl ester of 2,5-dihydroxycinnamic acid. It has a role as a human urinary metabolite, a plant metabolite, a geroprotector and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a cinnamate ester, a member of hydroquinones and a methyl ester.

Properties of METHYL 2,5-DIHYDROXYCINNAMATE

Melting point: 178-180°C
Density  1.318±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  0.1 M NaOH: soluble
form  crystalline
color  yellow
Water Solubility  Soluble in methanol or 0.1M NaOH. Insoluble in water
CAS DataBase Reference 63177-57-1(CAS DataBase Reference)

Safety information for METHYL 2,5-DIHYDROXYCINNAMATE

Signal word Warning
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H301:Acute toxicity,oral
H311:Acute toxicity,dermal
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H331:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for METHYL 2,5-DIHYDROXYCINNAMATE

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