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HomeProduct name listAdenosine 5'-monophosphate

Adenosine 5'-monophosphate

Synonym(s):5′-Adenylic Acid;Adenosine 5′-monophosphate;AMP

  • CAS NO.:61-19-8
  • Empirical Formula: C10H14N5O7P
  • Molecular Weight: 347.22
  • MDL number: MFCD00005750
  • EINECS: 200-500-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 15:53:33
Adenosine 5'-monophosphate Structural

What is Adenosine 5'-monophosphate?

Description

Adenosine-5'-monophosphoric acid is a nucleotide that is synthesized from adenosine triphosphate and inosine monophosphate. Adenosine-5'-monophosphoric acid is an important molecule in the body because it is a substrate for cyclic AMP, which regulates many cellular processes. Adenosine-5'-monophosphoric acid also has biochemical properties that are similar to those of the neurotransmitter serotonin and it can activate the 5-HT2 receptors.

Chemical properties

colorless to white crystalline powder

The Uses of Adenosine 5'-monophosphate

antiasthmatic

The Uses of Adenosine 5'-monophosphate

vasodilator, neuromodulator

The Uses of Adenosine 5'-monophosphate

A useful ligand determinant that facilitates the binding of APS reductase inhibitors.

The Uses of Adenosine 5'-monophosphate

Adenosine 5'-monophosphate is a nucleotide (building blocks of nucleic acid) added to skin care products to bind water and moisture.

The Uses of Adenosine 5'-monophosphate

Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.

Definition

ChEBI: A purine ribonucleoside 5'-monophosphate having adenine as the nucleobase.

Background

Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.

What are the applications of Application

Adenosine phosphate (Vitamin B8) is a useful ligand determinant that facilitates the binding of APS reductase inhibitors

Indications

For nutritional supplementation, also for treating dietary shortage or imbalance

brand name

Adenyl (Wyeth-Ayerst); My-BDen (Bayer.

Biological Activity

adenosine 5'-monophosphate is an ester of phosphoric acid with the nucleoside adenosine.

Pharmacokinetics

Adenosine monophosphate, also known as 5'-adenylic acid and abbreviated AMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside adenosine. AMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase adenine. AMP is used as a dietary supplement to boost immune activity, and is also used as a substitute sweetener to aid in the maintenance of a low-calorie diet.

Safety Profile

Slightly toxic by intraperitoneal route. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of PO, and NOx.

Metabolism

Not Available

Properties of Adenosine 5'-monophosphate

Melting point: 178-185 °C
Boiling point: 798.5±70.0 °C(Predicted)
Density  2.32±0.1 g/cm3(Predicted)
FEMA  4224 | ADENOSINE MONOPHOSPHATE; MONOSODIUM, OR DISODIUM ADENYLATE
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  H2O: with addition of mild alkalisoluble
form  Crystalline Powder
pka 3.8, 6.2(at 25℃)
color  Colorless to white
Water Solubility  Soluble in water.
Merck  14,158
Stability: Hygroscopic
InChI InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
CAS DataBase Reference 61-19-8(CAS DataBase Reference)
EPA Substance Registry System 5'-Adenylic acid (61-19-8)

Safety information for Adenosine 5'-monophosphate

Computed Descriptors for Adenosine 5'-monophosphate

InChIKey UDMBCSSLTHHNCD-KQYNXXCUSA-N
SMILES P(OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H](O)[C@@H]1O)(O)(O)=O

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