Adenosine 5'-monophosphate
Synonym(s):5′-Adenylic Acid;Adenosine 5′-monophosphate;AMP
- CAS NO.:61-19-8
- Empirical Formula: C10H14N5O7P
- Molecular Weight: 347.22
- MDL number: MFCD00005750
- EINECS: 200-500-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is Adenosine 5'-monophosphate?
Description
Adenosine-5'-monophosphoric acid is a nucleotide that is synthesized from adenosine triphosphate and inosine monophosphate. Adenosine-5'-monophosphoric acid is an important molecule in the body because it is a substrate for cyclic AMP, which regulates many cellular processes. Adenosine-5'-monophosphoric acid also has biochemical properties that are similar to those of the neurotransmitter serotonin and it can activate the 5-HT2 receptors.
Chemical properties
colorless to white crystalline powder
The Uses of Adenosine 5'-monophosphate
antiasthmatic
The Uses of Adenosine 5'-monophosphate
vasodilator, neuromodulator
The Uses of Adenosine 5'-monophosphate
A useful ligand determinant that facilitates the binding of APS reductase inhibitors.
The Uses of Adenosine 5'-monophosphate
Adenosine 5'-monophosphate is a nucleotide (building blocks of nucleic acid) added to skin care products to bind water and moisture.
The Uses of Adenosine 5'-monophosphate
Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.
Definition
ChEBI: A purine ribonucleoside 5'-monophosphate having adenine as the nucleobase.
Background
Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
What are the applications of Application
Adenosine phosphate (Vitamin B8) is a useful ligand determinant that facilitates the binding of APS reductase inhibitors
Indications
For nutritional supplementation, also for treating dietary shortage or imbalance
brand name
Adenyl (Wyeth-Ayerst); My-BDen (Bayer.
Biological Activity
adenosine 5'-monophosphate is an ester of phosphoric acid with the nucleoside adenosine.
Pharmacokinetics
Adenosine monophosphate, also known as 5'-adenylic acid and abbreviated AMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside adenosine. AMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase adenine. AMP is used as a dietary supplement to boost immune activity, and is also used as a substitute sweetener to aid in the maintenance of a low-calorie diet.
Safety Profile
Slightly toxic by intraperitoneal route. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of PO, and NOx.
Metabolism
Not Available
Properties of Adenosine 5'-monophosphate
Melting point: | 178-185 °C |
Boiling point: | 798.5±70.0 °C(Predicted) |
Density | 2.32±0.1 g/cm3(Predicted) |
FEMA | 4224 | ADENOSINE MONOPHOSPHATE; MONOSODIUM, OR DISODIUM ADENYLATE |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | H2O: with addition of mild alkalisoluble |
form | Crystalline Powder |
pka | 3.8, 6.2(at 25℃) |
color | Colorless to white |
Water Solubility | Soluble in water. |
Merck | 14,158 |
Stability: | Hygroscopic |
InChI | InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1 |
CAS DataBase Reference | 61-19-8(CAS DataBase Reference) |
EPA Substance Registry System | 5'-Adenylic acid (61-19-8) |
Safety information for Adenosine 5'-monophosphate
Computed Descriptors for Adenosine 5'-monophosphate
InChIKey | UDMBCSSLTHHNCD-KQYNXXCUSA-N |
SMILES | P(OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H](O)[C@@H]1O)(O)(O)=O |
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